Product phospholipids -phospholipid-peg-customization

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Catalog	name	Description	price
R-DS-0010	DSPE-PEG-APRPG(ALA Pro Arg Pro Gly)	1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-Polyethylene glyco-APRPG(ALA Pro Arg Pro Gly),APRPG(ALA Pro Arg Pro Gly),namely alanine proline arginine proline glycine sequence,can specifically act on the neovascularization site of tumor,and can be used as a probe to actively target the neovascularization.Aprpg modified liposomes are beneficial to deliver the encapsulated drugs to the vasculogenic vasculature system.The anti-tumor angiogenesis therapy with aprpg modified liposome can target almost all solid tumors actively without drug tolerance.It is a new and efficient anti-tumor method.	price>
R-DS-0097	HE2-PEG2000-DSPE	DSPE-PEG peptide customization-phospholipid service Ruixi Biotechnology Co.,Ltd. is a well-known phospholipid and PEG phospholipid supplier in China. Our laboratory has been committed to developing more dspe-peg-x derivatives.DSPE-PEG is a kind of long-term liposome material.It is modified with various active targeting materials or therapeutic materials or adjuvant treatment materials at the end of PEG,which is widely used in scientific research In the field.	price>
R-DS-0011	DSPE-PEG-VIP(vasoactive intestinal peptide)	Vasoactive intestinal peptide (VIP) is a basic peptide composed of 28 amino acid residues.It belongs to the gastrin/VIP family of gastrointestinal peptide hormones.It is widely distributed in the body,and has high content in the gastrointestinal tract,central and peripheral nerve endings,and has a wide range of physiological functions.	price>
R-DS-0098	DSPE-PEG-FGF-21	A modified human FGF-21 polypeptide consists of SEQ ID No: 1,SEQ ID No: 2,SEQ ID No: 3,SEQ ID No: 4 with methionine fused at the N-terminal,SEQ ID No: 5,SEQ ID No: 6 or SEQ ID with methionine fused at the N-terminal The modified human FGF-21 peptide has the biological activity of at least one FGF-21,and the unnatural coding amino acid is selected from para substituted phenylalanine,ortho substituted phenylalanine and meta substituted phenylalanine.	price>
R-DS-1111	DSPE-PEG-PTP(KTLLPTP)	PTP (ktllptp) specifically binds to pancreatic cancer cells.Proteomic analysis showed that PTP was targeted by specifically binding to plectin-1,which was mistakenly located on the cell membrane surface during the occurrence of pancreatic cancer.	price>
R-DS-0099	DSPE-PEG-ApoL1	APOL1 encodes a secreted high density lipoprotein(apolipoprotein L1) which binds to apolipoprotein A-I.Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL.It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body,as well as in reverse cholesterol transport from peripheral cells to the liver.Several different transcript variants encoding different isoforms have been found for APOL1.	price>
R-DS-0100	GRF-PEG-DSPE	Growth hormone releasing factor (GRF),also known as growth hormone releasing hormone (GHRH),is a kind of bioactive polypeptide existing in vertebrates.It is synthesized and secreted by hypothalamus and plays an important role in the growth,development and metabolism of vertebrates,As a positive regulator of pituitary growth hormone (GH),it can specifically induce the synthesis and secretion of growth hormone,and increase the level of GH in animal organs.	price>
R-DS-0101	T-20-PEG-DSPE	Like other peptide drugs,T-20 also has short half-life and poor stability in vivo.In order to obtain anti AIDS polypeptide with long efficacy and high stability,the peptide drug T-20 was modified by PEG (polyethylene glycol) and glycosylation by introducing selective amino acid sites(Cys SH) into the non active domain of the peptide through chemical synthesis,combined with organic synthesis and enzymatic synthesis technology.	price>
R-C-0102	DSPE-PEG2000-RVG29PPP(D-RVG29)	Rabies virus is a natural neurotropic virus.Its capsid contains a neurogenic protein (RVG),which can be specifically recognized by the nicotinic acetylcholine receptor (nAChR) on the surface of nerve cells.Under the action of RVG,rabies virus can easily cross the blood-brain barrier,invade brain tissue and sacred center,and cause rabies,The 29 amino acid sequence of RVG29 (YTIWMPENPRPGTPCDIFTNSRGKRASNG) can also be specifically recognized by nAChR.Liu et al.and Gong et al.T bonded RVG29 to polyamide amine dendrimer (PAMAM) and poly (ethylene amine) (PEI) to support and transport nucleic acid drugs,PAMAM and PE modified by RVG29 could pass through the BBB model,but could deliver cytotoxic anticancer drugs to pus.	price>
R-C-0103	DSPE-PEG2000-OME(D-OME)	To study the targeting effect of a novel ligand RVG29 modified liposome on gliomas in vitro.DSPE-PEG2000-RVG29 PPP (D-RVG29) was prepared by organic phase synthesis method,and liposomes were prepared by membrane dispersion method,The addition of DSPE-PEG2000-OME (D-OME) into the liposome formulation can make D-RVG29 modified liposomes have better particle size and distribution range.The uptake of D-RVG29 modified liposomes by C6 cells is stronger than that of unmodified d-rvg29 liposomes.There is no significant difference in the uptake intensity of the two liposomes by HeLa cells.D-OME can improve the stability of D-RVG29 modified liposomes,D-RVG29 modified liposome has the targeting ability of glioma cells in vitro.	price>

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