Product phospholipids -phospholipid-peg-customization

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Catalog	name	Description	price
R-DS-0100	GRF-PEG-DSPE	Growth hormone releasing factor (GRF),also known as growth hormone releasing hormone (GHRH),is a kind of bioactive polypeptide existing in vertebrates.It is synthesized and secreted by hypothalamus and plays an important role in the growth,development and metabolism of vertebrates,As a positive regulator of pituitary growth hormone (GH),it can specifically induce the synthesis and secretion of growth hormone,and increase the level of GH in animal organs.	price>
R-DS-0101	T-20-PEG-DSPE	Like other peptide drugs,T-20 also has short half-life and poor stability in vivo.In order to obtain anti AIDS polypeptide with long efficacy and high stability,the peptide drug T-20 was modified by PEG (polyethylene glycol) and glycosylation by introducing selective amino acid sites(Cys SH) into the non active domain of the peptide through chemical synthesis,combined with organic synthesis and enzymatic synthesis technology.	price>
R-C-0102	DSPE-PEG2000-RVG29PPP(D-RVG29)	Rabies virus is a natural neurotropic virus.Its capsid contains a neurogenic protein (RVG),which can be specifically recognized by the nicotinic acetylcholine receptor (nAChR) on the surface of nerve cells.Under the action of RVG,rabies virus can easily cross the blood-brain barrier,invade brain tissue and sacred center,and cause rabies,The 29 amino acid sequence of RVG29 (YTIWMPENPRPGTPCDIFTNSRGKRASNG) can also be specifically recognized by nAChR.Liu et al.and Gong et al.T bonded RVG29 to polyamide amine dendrimer (PAMAM) and poly (ethylene amine) (PEI) to support and transport nucleic acid drugs,PAMAM and PE modified by RVG29 could pass through the BBB model,but could deliver cytotoxic anticancer drugs to pus.	price>
R-C-0103	DSPE-PEG2000-OME(D-OME)	To study the targeting effect of a novel ligand RVG29 modified liposome on gliomas in vitro.DSPE-PEG2000-RVG29 PPP (D-RVG29) was prepared by organic phase synthesis method,and liposomes were prepared by membrane dispersion method,The addition of DSPE-PEG2000-OME (D-OME) into the liposome formulation can make D-RVG29 modified liposomes have better particle size and distribution range.The uptake of D-RVG29 modified liposomes by C6 cells is stronger than that of unmodified d-rvg29 liposomes.There is no significant difference in the uptake intensity of the two liposomes by HeLa cells.D-OME can improve the stability of D-RVG29 modified liposomes,D-RVG29 modified liposome has the targeting ability of glioma cells in vitro.	price>
R-DS-0012	DSPE-PEG-THRPPMWSPVWP	Liposomes have the advantages of low toxicity,easy preparation,and can be used as the carrier of water-soluble drugs and lipid soluble drugs.It can be used in a variety of drug delivery routes,improve the stability of drugs and achieve targeted drug delivery.However,when liposomes enter the body,due to the specific conditioning effect of plasma opsonin on liposomes and the nonspecific hydrophobic interaction between reticuloendothelial system (RES) cells and liposomes,it is easy to be absorbed and cleared by res cells.The half-life of liposomes in blood circulation is short (generally 30 min),and its active targeting and stability are poor,so its application is limited.	price>
R-DS-0013	DSPE-PEG-FSHB(QCHCGKCDSDSTDCT)	DSPE-PEG-FSHB(QCHCGKCDSDSTDCT),Follicle stimulating hormone (FSH) and its receptor (FSHR) binding fragment fshb (qchcgkcdsdstdct,fshl81-95),a peptide fragment of FSH,was used as a targeting head group J.the constructed FSHR targeting drug delivery system had good targeting effect on FSHR positive ovarian cancer cells.	price>
R-DS-0014	DSPE-PEG-NYZL1（Asn-Tyr-Glx-Leu）	The polypeptide nyzl1 (ASN Tyr GLX Leu) can specifically bind to bladder cancer tissues and cells,and has significant binding specificity.	price>
R-DS-0015	DSPE-PEG-HAIYPRH	T7 (haiyprh) is a short peptide screened by phage display technology,which can specifically bind to tr with a binding constant as high as 10 nmol-l.moreover, due to different binding sites,endogenous TF will not inhibit,but will promote the specific binding of T7 modified nanoparticles to TfR.Therefore,T7 is more suitable as a target molecule.	price>
R-PL-0163	DSPE-PEG-PFP	1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(polyethylene glycol)-Pentafluorophenyl,DSPE-PEG-PFP from ruixi Triblock copolymer DSPE-PEG-PFP .The nanoscale structures created from block copolymers could potentially be used for creating devices for use in computer memory, nanoscale-templating and nanoscale separations.Polyglutamic acid is a polymer of the amino acid glutamic acid.	price>
R-DS-0016	DSPE-PEG-SP94	Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology.It can be customized to synthesize various kinds of peptide polyethylene glycol (PEG)-DSPE reagents,which are used as active targeting materials,therapeutic materials or auxiliary therapeutic materials,and are widely used in scientific research.	price>

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