DSPE-PEG2000-RVG29PPP(D-RVG29)
1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene-glycol-RVG29PPP(D-RVG29)
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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R-C-0102 | 50mg | 1140.00 | + Add to cart |
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Product description
Rabies virus is a natural neurotropic virus.Its capsid contains a neurogenic protein (RVG),which can be specifically recognized by the nicotinic acetylcholine receptor (nAChR) on the surface of nerve cells.Under the action of RVG,rabies virus can easily cross the blood-brain barrier,invade brain tissue and sacred center,and cause rabies,The 29 amino acid sequence of RVG29 (YTIWMPENPRPGTPCDIFTNSRGKRASNG) can also be specifically recognized by nAChR.Liu et al.and Gong et al.T bonded RVG29 to polyamide amine dendrimer (PAMAM) and poly (ethylene amine) (PEI) to support and transport nucleic acid drugs,PAMAM and PE modified by RVG29 could pass through the BBB model,but could deliver cytotoxic anticancer drugs to pus.
Appearance | Off-white/brown solid or viscous liquid depends on molecular weight |
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PEG Molecular Weight | 1000,2000,3400,5000,10000 Dalton |
substitution by NMR | >95% |
PDI by GPC | <1.5 |
Solubility | Organic solvents |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 2 weeks |
Stability | 1 year |
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