Product apis-nf-kb

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Catalog	name	Description	price
R-R-1289	Sulfuretin CAS No.120-05-8	Sulfuretin/CAS No.120-05-8 inhibits the inflammatory response by suppressing the NF-κB pathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC50 of 13.64 μM.	price>
R-R-1290	FW1256 CAS No.117089-08-4	FW1256/CAS No.117089-08-4 is a phenyl analogue and a slow-releasing hydrogen sulfide (H2S) donor. FW1256 inhibits NF-κB activity and induces cell apoptosis. FW1256 exerts potent anti-inflammatory effects and has the potential for cancer and cardiovascular disease treatment.	price>
R-R-1291	Armepavine CAS No.524-20-9	Armepavine/CAS No.524-20-9, an active compound from Nelumbo nucifera, exerts not only anti-inflammatory effects on human peripheral blood mononuclear cells, but also immunosuppressive effects on T lymphocytes and on lupus nephritic mice. Armepavine inhibits TNF-α-induced MAPK and NF-κB signaling cascades.	price>
R-R-1292	Valencene CAS No.4630-07-3	Valencene/CAS No.4630-07-3 is a sesquiterpene isolated from Cyperus rotundus, possesses antiallergic, antimelanogenesis, anti-infammatory, and antioxidant activitivies. Valencene inhibits the exaggerated expression of Th2 chemokines and proinflammatory chemokines through blockade of the NF-κB pathway. Valencene is used to flavor foods and drinks.	price>
R-R-1293	Catalposide CAS No.6736-85-2	Catalposide/CAS No.6736-85-2, an iridoid glycoside that could be isolated from Catalpa ovate G. Don (Bignoniaceae), inhibits TNF-α, IL-1β, and IL-6 productions and NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages.	price>
R-R-1294	Deoxyelephantopin CAS No.29307-03-7	Deoxyelephantopin/CAS No.29307-03-7, a natural bioactive sesquiterpene lactone from Elephantopus scaber, has shown promising anticancer effects against a broad spectrum of cancers. Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling.	price>
R-R-1295	Demethyleneberberine CAS No.25459-91-0	Demethyleneberberine/CAS No.25459-91-0 is a natural mitochondria-targeted antioxidant. Demethyleneberberine alleviates mice colitis and inhibits the inflammatory responses by inhibiting NF-κB pathway and regulating the balance of Th cells. Demethyleneberberine could serve as a AMPK activator for treating non-alcoholic fatty liver disease (NAFLD).	price>
R-R-1296	Rubiadin-1-methyl ether CAS No.7460-43-7	Rubiadin-1-methyl ether/CAS No.7460-43-7 is a natural anthraquinone isolated from Morinda officinalis How, and inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nuclear translocation of p65.	price>
R-R-1297	Chelidonic acid CAS No.99-32-1	Chelidonic acid/CAS No.99-32-1 is a component of Chelidonium majus L., used as an antimicrobial. Chelidonic acid also shows anti-inflammatory activity. Chelidonic acid has potential to inhibit IL-6 production by blocking NF-κB and caspase-1. Chelidonic acid is a glutamate decarboxylase inhibitor, with a Ki of 1.2 μM.	price>
R-R-1298	Demethyleneberberine chloride CAS No.16705-03-6	Demethyleneberberine chloride/CAS No.16705-03-6 is a natural mitochondria-targeted antioxidant. Demethyleneberberine chloride alleviates mice colitis and inhibits the inflammatory responses by inhibiting NF-κB pathway and regulating the balance of Th cells. Demethyleneberberine chloride could serve as a AMPK activator for researching non-alcoholic fatty liver disease (NAFLD).	price>

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