Product apis-nf-kb

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Catalog	name	Description	price
R-C-2156	Licochalcone D CAS:144506-15-0	Licochalcone D,a flavonoid compound mainly existing in the root of Glycyrrhiza inflate,is a potent inhibitor of NF-kappaB(NF-κB)p65.Licochalcone D possesses antioxidant,anti-inflammatory,anti-cancer properties.	price>
R-C-2157	Licochalcone B CAS:58749-23-8	Licochalcone B has antitumor,antimetastatic,cardioprotective,antioxidant, antiapoptotic,and anti-inflammatory effects,it can significantly inhibit LPS-induced phosphorylation at serine 276 and transcriptional activation of NF-KB. Licochalcone B can protect the liver from carbon tetrachloride(CCl4)-induced injury,the protection may be due to inhibition of p38 and NFκB signaling,which subsequently reduces inflammation in the liver.	price>
R-C-2158	Myrislignan CAS: 171485-39-5	Myrislignan has anti-inflammatory,and anti-cancer activities,it inhibited NF-κB signalling pathway activation,inhibited the proliferation of A549 cells in a dose-and time-dependent manner,it also significantly induced apoptosis and cell cycle arrest in A549 cells.	price>
R-C-2160	Withaferin A CAS:5119-48-2	Withaferin A is a steroidal lactone present in W.somnifera that at 2-25μM has been shown to bind to and induce aggregation of vimentin intermediate filaments in cultured endothelial cells and fibroblasts,causing apoptosis.	price>
R-C-2321	Praeruptorin A CAS:73069-27-9	Praeruptorin A is a main bioactive constituent of Peucedanum praeruptorum(also known as Bai-Hua Qian Hu).Praeruptorin A exerts anti-inflammatory effects in vitro through inhibition of NF-κB activation.	price>
R-C-2322	Ginsenoside Rd CAS: 52705-93-8	Ginsenoside Rd(Panaxoside Rd,Sanchinoside Rd),a minor ginseng saponin,has several pharmacological activities such as immunosuppressive activity,anti-inflammatory activity,immunological adjuvant,anti-cancer activity and wound-healing activity.Ginsenoside Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC50 of 12.05±0.82 μM in HepG2 cells.Ginsenoside Rd inhibits expression of COX-2 and iNOS mRNA.Ginsenoside Rd also inhibits Ca2+ influx.	price>
R-C-3013	ML-385 CAS：846557-71-9	ML385 inihbits the activity of the Nrf2 transcription factor by binding to Neh1, a CNC-bZIP domain that allows Nrf2 to heterodimerize with small Maf proteins, blocking NRF2 transcriptional activity. Only for scientific research, not for human body.	price>

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