Product apis-nf-kb

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Catalog	name	Description	price
R-R-1269	Cyclo(his-pro) TFA CAS No.936749-56-3	Cyclo(his-pro) TFA (Cyclo(histidyl-proline) TFA)/CAS No.936749-56-3 is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone. Cyclo(his-pro) TFA could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) TFA can cross the brain-blood-barrier and affect diverse inflammatory and stress responses.	price>
R-R-1270	N-Acetyldopamine dimer-2 CAS No.916888-49-8	N-Acetyldopamine dimer-2 (compound 2)/CAS No.916888-49-8 is a N-acetyldopamine dimer that can be isolated from the yellow powder form Periostracum Cicadae with antioxidant and anti-inflammatory activities. N-Acetyldopamine dimer-2 inhibits oxidized low-density lipoprotein (LDL) oxidation, ROS generation, NO production, and NF-κB activity.	price>
R-R-1271	Lidocaine hydrochloride hydrate CAS No.6108-05-0	Lidocaine (Lignocaine) hydrochloride hydrate/CAS No.6108-05-0 inhibits sodium channels involving complex voltage and using dependence. Lidocaine hydrochloride hydrate decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine hydrochloride hydrate is an amide derivative and has potential for the research of ventricular arrhythmia.	price>
R-R-1272	Aristolochic acid A CAS No.313-67-7	Aristolochic acid A (Aristolochic acid I; TR 1736)/CAS No.313-67-7 is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A reduces BLCAP gene expression in human cell lines.	price>
R-R-1273	Gypenoside L CAS No.94987-09-4	Gypenoside L/CAS No.94987-09-4 is a saponin that can be found in Gynostemma pentaphyllum. Gypenoside L increases the SA-β-galactosidase activity, promotes the production of senescence-associated secretory cytokines. Gypenoside L also can activate p38 and ERK MAPK pathways and NF-κB pathway to induce senescence. Gypenoside L exhibits anti-tumor and anti-inflammatory activities.	price>
R-R-1274	Phorbol 12-myristate 13-acetate CAS No.16561-29-8	Phorbol 12-myristate 13-acétate (PMA)/CAS No.16561-29-8, un ester de phorbol, est un activateur double SphK et protéine kinase C (PKC).	price>
R-R-1275	Pentagamavunon-1 CAS No.27060-70-4	Pentagamavunon-1 (PGV-1)/CAS No.27060-70-4, a Curcumin analog with oral activity, targets on several molecular mechanisms to induce apoptosis including inhibition of angiogenic factors cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF). PGV-1 inhibits NF-κB activation.	price>
R-R-1276	Ethyl Caffeate CAS No.102-37-4	Ethyl Caffeate/CAS No.102-37-4 is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin.	price>
R-R-1277	Muscone CAS No.541-91-3	Muscone/CAS No.541-91-3 is the main active monomer of traditional Chinese medicine musk. Muscone inhibits NF-κB and NLRP3 inflammasome activation. Muscone remarkably decreases the levels of inflammatory cytokines (IL-1β, TNF-α and IL-6), and ultimately improves cardiac function and survival rate.	price>
R-R-1278	Sulforaphene CAS No.592-95-0	Sulforaphene/CAS No.592-95-0, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF‐κB and other signals.	price>

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