Product apis-neuronal-signaling

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Catalog	name	Description	price
R-C-2793	RuBi-Nicotine CAS:1256362-30-7	Ruthenium-bisbipyridine-caged nicotine,excitable by irradiation with visible light.Undergoes rapid photolysis to release nicotine(<20 ns);exhibits a high quantum yield.Induces action potential propagation in Retzius neurons of leech ganglia with no detectable toxicity at a concentration of 1mM.	price>
R-C-2794	VU 0360223 CAS:1274859-33-4	Potent negative allosteric modulator of mGlu5(IC50=61nM).Displays no activity at mGlu1-4 and mGlu7-8.	price>
R-C-2795	Alcaftadine (R89674) CAS:147084-10-4	Alcaftadine(R89674)is a histamine H1 receptor antagonist,which is used to prevent eye irritation brought on by allergic conjunctivitis.Alcaftadine is a broad-spectrum antihistamine displaying a high affinity for histamine H1 and H2 receptors and a lower affinity for H4 receptors.Alcaftadine also exhibits modulatory action on immune cell recruitment and mast cell stabilizing effects.	price>
R-C-2796	Maropitant CAS:147116-67-4	Maropitant is a neurokinin(NK1)receptor antagonist.IC50 value:Target:NK1 receptor Maropitant is the first NK1 receptor antagonist developed to treat and prevent emesis in dogs.	price>
R-C-2798	Pizotifen CAS:15574-96-6	Pizotifen is a serotonin antagonist which acts mainly at the 5-HT1,5-HT2A,and 5HT2C receptors with some antihistamine activity.	price>
R-C-2799	Licofelone (ML3000) CAS:156897-06-2	Licofelone(ML-3000)is a dual COX/5-lipoxygenase(5-LOX)inhibitor(IC50=0.21/0.18μM,respectively) for the treatment of osteoarthritis.Licofelone exerts anti-inflammatory and anti-proliferative effects.Licofelone induces apoptosis,and decreases the production of proinflammatory leukotrienes and prostaglandins.	price>
R-C-2801	ML352 CAS:1649450-12-3	The neurotransmitter acetylcholine(ACh)plays a critical role in autonomic function,motor control,attention,learning, and memory,and reward.ML352 is a novel,noncompetitive inhibitor of the presynaptic choline transporter.	price>
R-C-2802	MSPG CAS:169209-64-7	Relatively non-selective antagonist of presynaptic mGlu receptors in neonatal rat spinal cord and adult rat cerebrocortical mGlu receptors.	price>
R-C-2803	MTPG CAS:169209-66-9	MTPG is a group II/group III mGlu antagonist,showing selectivity for group II in electrophysiological studies.MTPG is a potent antagonist for(1S,3S)-ACPD-sensitive receptors;preference for group II mGluR.	price>
R-C-2807	SDZ NKT 343 CAS:180046-99-5	SDZ NKT 343 is a highly selective human tachykinin NK1 receptor antagonist that antagonizes SP-induced Ca2+ efflux in vitro and inhibits mechanical hyperalgesia in vivo.	price>

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