Product apis-neuronal-signaling

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Catalog	name	Description	price
R-C-2475	Revefenacin CAS:864750-70-9	Revefenacin(TD-4208;GSK1160724)is a potent mAChR antagonist;has a high affinity on M3 receptor with a Ki of 0.18nM.	price>
R-C-2476	Diphemanil Methylsulfate CAS:62-97-5	Diphemanil Methylsulfate is a quaternary ammonium anticholinergic,it binds muscarinic acetycholine receptors(mAchR).	price>
R-C-2477	Glycopyrrolate CAS:596-51-0	Glycopyrrolate(Glycopyrronium,Robinul,Gastrodyn)is a muscarinic antagonist used as an antispasmodic,in some disorders of the gastrointestinal tract,and to reduce salivation with some anesthetics.	price>
R-C-2478	Tropisetron CAS: 89565-68-4	Tropisetron(SDZ-ICS-930 free base)is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1±0.9nM for 5-HT3 receptor.	price>
R-C-2479	Thonzylamine CAS:91-85-0	Thonzylamine is an orally active H1 histamine receptor antagonist,exhibits good antihistaminic and antianaphylactic properties.Thonzylamine can be used for the research of hypersensitivity diseases,nasal congestion,allergic conjunctivitis and other allergic diseases.	price>
R-C-2480	Caulophylline (N-Methylcytisine) CAS:486-86-2	Caulophylline(N-Methylcytisine,Caulophyllin,NMC)is a tricyclic quinolizidine alkaloid with anti-inflammatory activities.Caulophylline binds to nicotinic acetylcholine receptors(nAChR)from squid optical ganglia with Kd of 50nM. Caulophylline significantly reduces myeloperoxidase(MPO)activity,blocks the activation of NF-κB by inhibiting IκB and IKK phosphorylation.	price>
R-C-2489	BRL 54443 CAS:57477-39-1	BRL 54443 is a potent 5-HT1E/1F receptor agonist(Ki values are 1.1nM and 0.7 nM respectively);displays>30-fold selectivity over other 5-HT and dopamine receptors.	price>
R-C-2541	Oxiracetam CAS：62613-82-5	Oxiracetam is a cyclic derivative of γ-aminobutyric acid(GABA)which has been commonly used as nootropic drug to treat cognitive impairments.	price>
R-C-2542	Prasugrel CAS：150322-43-3	Prasugrel(PCR 4099),a thienopyridine and prodrug,inhibits platelet function.Prasugrel is an orally active and potent P2Y12 receptor antagonist,and inhibits ADP-induced platelet aggregation.	price>
R-C-2543	Agomelatine (S-20098) CAS:138112-76-2	Agomelatine(S-20098)is a specific agonist of MT1 and MT2 receptors with Kis of 0.1,0.06,0.12, and 0.27nM for CHO-hMT1,HEK-hMT1,CHO-hMT2,and HEK-hMT2,respectively.Agomelatine is a selective 5-HT2C receptor antagonist with pKis of 6.4 and 6.2 at native(porcine)and cloned, human 5-HT2C receptors, respectively.	price>

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