Product apis-neuronal-signaling

Home > products > apis> neuronal-signaling

Catalog	name	Description	price
R-C-2448	Acotiamide CAS:185106-16-5	Acotiamide(Acofide,Z388)is a novel acetylcholinesterase inhibitor with fundus-relaxing and gastroprokinetic properties.	price>
R-C-2452	PNU-120596 CAS：501925-31-1	PNU-120596(NSC 216666)is a potent and selective α7 nAChR positive allosteric modulator(PMA)with an EC50 of 216 nM.PNU-120596 is inactive against α4β2, α3β4,and α9α10 nAChRs.PNU-120596 has the potential for psychiatric and neurological disorders research.	price>
R-C-2453	BNC210 CAS：13589-06-5	BNC210(H-Ile-Trp-OH;IW-2143)is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.	price>
R-C-2454	VU0238441 CAS：85511-68-8	VU0238441 is a pan muscarinic acetylcholine receptor(mAChR)positive allosteric modulator(PAM)with EC50s of 3.2 μM,2.8μM,2.2μM,2.1μM,>10μM for M1,M2,M3,M5 and M4,respectively.	price>
R-C-2455	VU0119498 CAS：79183-37-2	VU0119498 is a pan Gq mAChR M1,M3,M5 positive allosteric modulator(PAM), with EC50s of 6.04,6.38,and 4.08µM,respectively.VU0119498 has antidiabetic activity.	price>
R-C-2457	VU0238429 CAS：1160247-92-6	VU 0238429 is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5(mAChR5 or M5),with an EC50 of 1.16μM.	price>
R-C-2458	JHU37152 CAS：2369979-67-7	JHU37152 is a potent and brain-penetrant DREADD agonist,with EC50s of 5 nM and 0.5 nM for hM3Dq and hM4Di DREADDs in HEK-293 cells,respectively. JHU37152 exhibits selective [3H]Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue.	price>
R-C-2459	JHU37160 CAS：2369979-68-8	JHU37160 is a potent and brain-penetrant DREADD agonist,with EC50s of 18.5 nM and 0.2 nM for hM3Dq and hM4Di DREADDs in HEK-293 cells,respectively.JHU37160 exhibits selective Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue.	price>
R-C-2460	Varenicline Tartrate (CP 526555-18) CAS：375815-87-5	Varenicline Tartrate(CP 526555;Champix)is a nicotinic receptor partial agonist; it stimulates nicotine receptors more weakly than nicotine itself does.	price>
R-C-2461	Bethanechol chloride CAS：590-63-6	Bethanechol chloride(Carbamyl-β-methylcholine chloride),a parasympathomimetic agent,is a mAChR agonist that exerts its effects via directly stimulating the mAChR(M1,M2,M3,M4,and M5)of the parasympathetic nervous system.	price>

...