Product apis-neuronal-signaling

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Catalog	name	Description	price
R-C-2544	Escitalopram oxalate CAS:219861-08-2	Escitalopram Oxalate is a furancarbonitrile that is one of the selective serotonin uptake inhibitors used as an antidepressant.As a selective serotonin reuptake inhibitor(SSRI),escitalopram blocks the reuptake of serotonin by neurons in the central nervous system(CNS),thereby potentiating CNS serotonergic activity.	price>
R-C-2545	Clemizole CAS:442-52-4	Clemizole is an H1 histamine receptor antagonist,is found to substantially inhibit HCV replication.The IC50 of Clemizole for RNA binding by NS4B is 24±1nM,whereas its EC50 for viral replication is 8µM.	price>
R-C-2546	J147 CAS:1146963-51-0	J-147 is an exceptionally potent,orally active, neuroprotective agent for cognitive enhancement.J-147 can readily pass the blood brain barrier(BBB).J-147 can inhibit monoamine oxidase B(MAO B)and the dopamine transporter with EC50 values of 1.88μM and 0.649μM,respectively.	price>
R-C-2547	NS11394 CAS:951650-22-9	NS-11394 is a drug which acts as a subtype-selective positive allosteric modulator at GABAA receptors,with selectivity for the α3 and α5 subtypes. NS11394 has a unique subtype-selective GABA(A)receptor profile and represents an excellent pharmacological tool to further understanding on the relative contributions of GABA(A)receptor subtypes in various therapeutic areas.	price>
R-C-2550	Muscimol HBr CAS:18174-72-6	Muscimol hydrobromide is a potent but toxic structural analog of g-aminobutyric acid(GABA),with a zwitterionic structure.	price>
R-C-2752	Radicicol CAS:496054-87-6	Radicicol is an inhibitor of Hsp90 with an IC50 value of 1μM.Radicicol binds to the ATPase domain of Hsp90 and prevents maturation of Hsp90 clients, leading to proteasomal degradation.Radicicol is an antifungal antibiotic with antimalarial activity,impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB.	price>
R-C-2774	Desloratadine CAS:100643-71-8	Desloratadine(Sch34117)is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine.Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities.	price>
R-C-2775	Rotundine CAS:483-14-7	Rotundine(L-tetrahydropalmatine,L-THP)is a selective dopamine D1 receptor antagonist with IC50 of 166nM.	price>
R-C-2778	Talipexole CAS：101626-70-4	Talipexole(B-HT920)is a dopamine agonist that has been proposed as an antiparkinsonian agent.	price>
R-C-2779	ARN2966 CAS：102212-26-0	ARN2966 is a potent post-transcriptional modulator of APP expression; reduces expression of APP with resultant lower production of Aβ.	price>

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