Product apis-jak-stat

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Catalog	name	Description	price
R-R-2345	Tyk2-IN-8 CAS No.2704587-24-4	Tyk2-IN-8/CAS No.2704587-24-4 is a selective Tyk-2 inhibitor with an IC50 of 5.7 nM for TYK2-JH2. Tyk2-IN-8 inhibits JAK1-JH1 with IC50 of 3.0 nM. Tyk2-IN-8 can be used for the research of autoimmune disease.	price>
R-R-2346	Filgotinib-d4 CAS No.2041095-50-3	Filgotinib-d4/CAS No.2041095-50-3 is the deuterium labeled Filgotinib. Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.	price>
R-R-2347	LFM-A13 CAS No.62004-35-7	LFM-A13/CAS No.62004-35-7 is a potent BTK, JAK2, PLK inhibitor, inhibits recombinant BTK, Plx1 and PLK3 with IC50s of 2.5 μM, 10 μM and 61 μM. LFM-A13 has antiproliferative activity and anticancer activity. LFM-A13 can be used in cancer-related research.	price>
R-R-2348	(3R,4S)-Tofacitinib CAS No.1092578-46-5	(3R,4S)-Tofacitinib/CAS No.1092578-46-5 is an less active enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.	price>
R-R-2349	Fosifidancitinib CAS No.1237168-58-9	Fosifidancitinib/CAS No.1237168-58-9 is a potent and selective inhibitor of JAK kinases 1/3. Fociatinib is used in studies of allergies, asthma and autoimmune diseases.	price>
R-R-2350	Nimucitinib CAS No.2740557-24-6	Nimucitinib/CAS No.2740557-24-6 is a Janus kinase (JAK) inhibitor.	price>
R-R-2351	(Rac)-Ruxolitinib-d9 CAS No.2469553-67-9	(Rac)-Ruxolitinib D9 ((Rac)-INCB18424 D9)/CAS No.2469553-67-9 is the deuterium labeled (Rac)-Ruxolitinib. (Rac)-Ruxolitinib is a JAK2 inhibitor.	price>
R-R-2352	JAK-IN-25 CAS No.2127110-22-7	JAK-IN-25 (compound 19)/CAS No.2127110-22-7 is a potent JAK inhibitor with IC50s of 6 nM, 21 nM, 8 nM, 1051 nM for TYK2, JAK1, JAK2, JAK3, respectively. JAK-IN-25 inhibits human whole blood IL-12 (HEB IL-12) with an IC50 of 28 nM. JAK-IN-25 has the potential for cancer research.	price>
R-R-2353	Lepzacitinib CAS No.2321488-47-3	Lepzacitinib/CAS No.2321488-47-3 is a Janus kinase inhibitor targeting to JAK 1/3. Lepzacitinib exhibits anti-inflammatory effect and inhibits atopic dermatitis and other skin diseases.	price>
R-R-2354	Dehydrocrenatidine CAS No.65236-62-6	Dehydrocrenatidine/CAS No.65236-62-6, a natural alkaloid, is a specific JAK inhibitor. Dehydrocrenatidine inhibits voltage-gated sodium channels and ameliorates mechanic allodia in a rat model of neuropathic pain.	price>

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