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Home > products > apis> gpcr-g-protein
Catalog name Description price
R-C-1945 PHCCC CAS:179068-02-1 PHCCC is a Group I mGluR antagonist with an IC50 of 3 μM.PHCCC is a selective positive modulator of mGlu4 receptor.Antiparkinsonian effect. price>
R-C-1949 Riociguat(BAY 63-2521) CAS : 625115-55-1 Riociguat is an oral stimulator of soluble guanylate cyclase(sGC)used in the treatment of pulmonary hypertension. price>
R-C-1981 Rimegepant (BMS-927711) CAS：1289023-67-1 Rimegepant(BMS-927711)is a highly potent,oral calcitonin gene-related peptide (CGRP)receptor antagonist with a Ki of 0.027nM and an IC50 of 0.14nM for hCGRP receptor. price>
R-C-1997 PD 168077 MALEATE CAS:630117-19-0 PD-168077 maleate is a selective dopamine D4 receptor agonist,with a Ki of 9 nM. price>
R-C-2013 Etrumadenant (AB928) CAS：2239273-34-6 AB928 is an orally bioavailable,selective dual adenosine receptor(A2aR/A2bR)antagonist.AB928 relieves adenosine-mediated immune suppression.AB928 has immunomodulatory and antitumor activities. price>
R-C-2021 MK-7246 CAS：1218918-62-7 MK-7246 is a potent and selective CRTH2(chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells)antagonist.MK-7246 is used for the treatment of respiratory diseases. price>
R-C-2025 AMG 837 CAS:865231-46-5 AMG 837 is a potent GPR40 agonist(EC50=13nM)with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. price>
R-C-2026 Nastorazepide CAS:209219-38-5 Nastorazepide(Z-360)is a selective,orally available,1,5-benzodiazepine-derivative gastrin/cholecystokinin 2(CCK-2)receptor antagonist with potential antineoplastic activity. price>
R-C-2034 PIPERIDOLATE CAS：82-98-4 Piperidolate is an antimuscarinic,inhibits intestinal cramp induced by acetylcholine(rats and dogs). price>
R-C-2037 QS11 CAS：944328-88-5 QS11 is an inhibitor of ARFGAP1(ADP-ribosylation factor GTPase-activating protein 1),with an EC50 of 1.5µM.QS11 modulates Wnt/β-catenin signaling through an effect on protein trafficking.QS11 inhibits migration of ARFGAP overexpressing breast cancer cells. price>