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Catalog name Description price
R-R-3627 Betaxolol hydrochloride CAS No.63659-19-8 Betaxolol Hydrochloride/CAS No.63659-19-8 is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma. price>
R-C-1929 AM966  CAS：1228690-19-4 AM966 is a high affinity,selective,oral LPA1-antagonist,inhibits LPA-stimulated intracellular calcium release(IC50=17nM). price>
R-C-1930 AM095 CAS: 1228690-36-5 AM095 is a potent LPA1 receptor antagonist because it inhibited GTPγS binding to Chinese hamster ovary(CHO)cell membranes overexpressing recombinant human or mouse LPA1 with IC50 values of 0.98 and 0.73μM,respectively,and exhibited no LPA1 agonism.Lysophosphatidic acid(LPA)is a bioactive phospholipid that signals through a family of at least six G protein-coupled receptors designated LPA1-6. LPA type 1 receptor(LPA1)exhibits widespread tissue distribution and regulates a variety of physiological and pathological cellular functions. price>
R-C-1945 PHCCC CAS:179068-02-1 PHCCC is a Group I mGluR antagonist with an IC50 of 3 μM.PHCCC is a selective positive modulator of mGlu4 receptor.Antiparkinsonian effect. price>
R-C-1949 Riociguat(BAY 63-2521) CAS : 625115-55-1 Riociguat is an oral stimulator of soluble guanylate cyclase(sGC)used in the treatment of pulmonary hypertension. price>
R-C-1981 Rimegepant (BMS-927711) CAS：1289023-67-1 Rimegepant(BMS-927711)is a highly potent,oral calcitonin gene-related peptide (CGRP)receptor antagonist with a Ki of 0.027nM and an IC50 of 0.14nM for hCGRP receptor. price>
R-C-1997 PD 168077 MALEATE CAS:630117-19-0 PD-168077 maleate is a selective dopamine D4 receptor agonist,with a Ki of 9 nM. price>
R-C-2013 Etrumadenant (AB928) CAS：2239273-34-6 AB928 is an orally bioavailable,selective dual adenosine receptor(A2aR/A2bR)antagonist.AB928 relieves adenosine-mediated immune suppression.AB928 has immunomodulatory and antitumor activities. price>
R-C-2021 MK-7246 CAS：1218918-62-7 MK-7246 is a potent and selective CRTH2(chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells)antagonist.MK-7246 is used for the treatment of respiratory diseases. price>
R-C-2025 AMG 837 CAS:865231-46-5 AMG 837 is a potent GPR40 agonist(EC50=13nM)with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. price>