Product apis-gpcr-g-protein

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Catalog	name	Description	price
R-R-3581	ST 1535 CAS No.496955-42-1	ST 1535/CAS No.496955-42-1 is a potent and orally active A2A adenosine receptor antagonist. ST 1535 shows antiparkinsonian activity and antitremorigenic effects. ST 1535 has the potential for the research of Parkinson disease.	price>
R-R-3582	Binodenoson CAS No.144348-08-3	Binodenoson (MRE-0470)/CAS No.144348-08-3 is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stress imaging.	price>
R-C-1883	SSR240612 CAS:464930-42-5	SSR240612 is a potent,and orally active specific non-peptide bradykinin B1 receptor antagonist,with Kis of 0.48 nM and 0.73nM for B1 kinin receptors of human fibroblast MRC5 and HEK cells expressing human B1 receptors,481nM and 358 nM for B2 receptors of guinea pig ileum membranes and CHO cells expressing human B1 receptor,respectively.	price>
R-R-3583	CL 316243 CAS No.138908-40-4	CL316243/CAS No.138908-40-4 is a highly potent selective β3-adrenoceptor agonist with a EC50 of 3 nM, but is an extremely poor to β1/2- receptors.CL316243 is a effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate. CL316243 has the potential for the treatment obesity, diabetes and urge urinary incontinence.	price>
R-R-3584	Propranolol CAS No.525-66-6	Propranolol/CAS No.525-66-6 is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively. Propranolol inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM. Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy.	price>
R-R-3585	Zenidolol hydrochloride CAS No.72795-01-8	Zenidolol (ICI-118551) hydrochloride/CAS No.72795-01-8 is a highly selective β2 adrenergic receptor antagonist, with Kis of 0.7, 49.5 and 611 nM for β2, β1 and β3 receptors, respectively.	price>
R-R-3586	BRL-44408 maleate CAS No.681806-46-2	BRL-44408 maleate/CAS No.681806-46-2 is an α2A-adrenoceptor antagonist (Ki: 8.5 nM). BRL-44408 maleate has antidepressant and analgesic activity. BRL-44408 also improves cecal ligation puncture (CLP)-induced acute lung injury.	price>
R-R-3587	Adenosine receptor antagonist 4 CAS No.133240-06-9	Adenosine receptor antagonist 4 (compound 2)/CAS No.133240-06-9 is an adenosine A1 receptor antagonist with a Ki of 101 nM for human A1 receptor.	price>
R-R-3588	FSCPX CAS No.156547-56-7	FSCPX/CAS No.156547-56-7 is a potent and selective irreversible antagonist of A1 adenosine receptor (A1AR), with low nanomolar potency for binding to the A1AR. FSCPX could modify the effect of NBTI, a nucleoside transport inhibitor, by reducing the interstitial adenosine level in the guinea pig atrium.	price>
R-R-3589	Salmeterol CAS No.89365-50-4	Salmeterol (GR33343X)/CAS No.89365-50-4 is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively.	price>

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