Product apis-gpcr-g-protein

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Catalog	name	Description	price
R-R-3588	FSCPX CAS No.156547-56-7	FSCPX/CAS No.156547-56-7 is a potent and selective irreversible antagonist of A1 adenosine receptor (A1AR), with low nanomolar potency for binding to the A1AR. FSCPX could modify the effect of NBTI, a nucleoside transport inhibitor, by reducing the interstitial adenosine level in the guinea pig atrium.	price>
R-R-3589	Salmeterol CAS No.89365-50-4	Salmeterol (GR33343X)/CAS No.89365-50-4 is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively.	price>
R-R-3590	Phenylacetylglycine CAS No.500-98-1	Phenylacetylglycine/CAS No.500-98-1 is a gut microbial metabolite that can activate β2AR. Phenylacetylglycine protects against cardiac injury caused by ischemia/reperfusion.	price>
R-R-3591	Dexmedetomidine hydrochloride CAS No.145108-58-3	Dexmedetomidine hydrochloride ((+)-Medetomidine hydrochloride)/CAS No.145108-58-3 is a potent, selective and orally active agonist of α2-adrenoceptor, with a Ki of 1.08 nM. Dexmedetomidine hydrochloride shows 1620-fold selectivity against α1-adrenoceptor. Dexmedetomidine hydrochloride exhibits anxiolysis, sedation, and modest analgesia effects.	price>
R-R-3592	Dobutamine hydrochloride CAS No.49745-95-1	Dobutamine hydrochloride/CAS No.49745-95-1 is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion.	price>
R-R-3593	Atomoxetine hydrochloride CAS No.82248-59-7	Atomoxetine (Tomoxetine) hydrochloride/CAS No.82248-59-7 is a selective noradrenaline reuptake inhibitor with Ki values of 5 nM, 77 nM and 1451 nM for norepinephrine (NE), serotonin (5-HT) and dopamine (DA) transporters, respectively. Atomoxetine hydrochloride is a potent Na+ channels (VGSCs) blocker. Atomoxetine hydrochloride can be used for attention-deficit hyperactivity disorder (ADHD) research.	price>
R-R-3594	Terazosin hydrochloride dihydrate CAS No.70024-40-7	Terazosin hydrochloride dihydrate/CAS No.70024-40-7 is a quinazoline derivative and a competitive and orally active α1-adrenoceptor antagonist. Terazosin hydrochloride dihydrate works by relaxing blood vessels and the opening of the bladder. Terazosin hydrochloride dihydrate has the potential for benign prostatic hyperplasia (BPH) and high blood pressure treatment.	price>
R-C-2255	Amarogentin CAS：21018-84-8	Amarogentin(AG),a secoiridoid glycoside mainly extracted from Swertia and Gentiana roots,exhibits anti-oxidative,anti-tumour,and anti-diabetic activities.Amarogentin is an agonist for the bitter taste receptor TAS2R1 and inhibits in LAD-2 cells substance P-induced production of newly synthesized TNF-α.Amarogentin induces apoptosis in human gastric cancer cells(SNU-16)through G2/M cell cycle arrest and PI3K/Akt signalling pathway.	price>
R-R-3595	Clonidine CAS No.4205-90-7	Clonidine/CAS No.4205-90-7 is an alpha 2-adrenergic agonist.	price>
R-R-3596	Tamsulosin CAS No.106133-20-4	Tamsulosin ((R)-(-)-YM12617 free base)/CAS No.106133-20-4 is an inhibitor of α1-adrenergic receptor. Tamsulosin is used for the research of prostatic hyperplasia. Tamsulosin attenuates abdominal aortic aneurysm growth in animal models.	price>

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