Product apis-gpcr-g-protein

Home > products > apis> gpcr-g-protein

Catalog	name	Description	price
R-R-2668	L-Glutamine-15N-1 CAS No.59681-32-2	L-Glutamine-15N-1/CAS No.59681-32-2 is the 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.	price>
R-R-2669	RO0711401 CAS No.714971-87-6	RO0711401/CAS No.714971-87-6 is a selective and orally active positive allosteric modulator of mGlu1 receptor with an EC50 of 56 nM.	price>
R-R-2670	Foliglurax monohydrochloride	Foliglurax monohydrochloride (PXT002331 monohydrochloride) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) , with an EC50 of 79 nM. Antiparkinsonian effect.	price>
R-R-2671	Basimglurant CAS No.802906-73-6	Basimglurant (RG7090)/CAS No.802906-73-6 is a potent, selective and orally available mGlu5 negative allosteric modulator with a Kd of 1.1 nM. Basimglurant is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-C-972	MS-275 cas:209783-80-2	MS-275 is an inhibitor of HDAC (histone deacetylase) that preferentially inhibits HDAC1(IC50=300 nM)over HDAC3(IC50=8 μM).However,MS-275 does not inhibit HDAC8 (IC50>100μM).MS-275 induces cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1),slowing cell growth,differentiation,and tumor development in vivo.Recent studies suggest that MS-275 may be particularly useful as an antineoplastic agent when combined with other drugs,like adriamycin,inhibitors of poly(ADP-ribose)polymerase(PARP),or inhibitors of heat shock protein 90 (Hsp90).	price>
R-R-2672	MSOP CAS No.66515-29-5	MSOP/CAS No.66515-29-5 is a selective group III metabotropic glutamate receptor antagonist with apparent KD of 51 μM for the L-AP4-sensitive presynaptic mGluR.	price>
R-R-2673	MPEP CAS No.96206-92-7	MPEP/CAS No.96206-92-7 is a potent, selective, noncompetitive, orally active and systemically active mGlu5 receptor antagonist, with an IC50 of 36 nM for completely inhibiting quisqualate-stimulated phosphoinositide (PI) hydrolysis. MPEP has anxiolytic-or antidepressant-like effects. MPEP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-R-2674	VU0650786 CAS No.1809085-30-0	VU0650786/CAS No.1809085-30-0 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM), with an IC50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents.	price>
R-R-2675	mGluR2 antagonist 1 CAS No.1432728-49-8	mGluR2 antagonist 1/CAS No.1432728-49-8 is a highly potent, orally bioavailable and selective class of mGluR2 negative allosteric modulator (IC50 of 9 nM) with excellent brain permeability.	price>
R-R-2676	L-Glutamine-15N CAS No.80143-57-3	L-Glutamine-15N/CAS No.80143-57-3 is the 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.	price>

...

163