Product apis-gpcr-g-protein

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Catalog	name	Description	price
R-R-2648	Calcium-Sensing Receptor Antagonists I CAS No.478963-79-0	Calcium-Sensing Receptor Antagonists I/CAS No.478963-79-0 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-R-2649	SB-423562 CAS No.351490-27-2	SB-423562/CAS No.351490-27-2 is a short-acting calcium-sensing receptor (CaR) antagonist. SB-423562 has the potential for osteoporosis research.	price>
R-R-2650	GSK3004774 CAS No.2138814-32-9	GSK3004774/CAS No.2138814-32-9 is a potent, nonabsorbable agonist of CaSR, with an pEC50 of 7.3, 6.6 and 6.5 for human, mouse and rat CaSR, respectively. GSK3004774 shows an EC50 of 50 nM for human CaSR.	price>
R-R-2651	Calindol hydrochloride CAS No.729610-18-8	Calindol hydrochloride/CAS No.729610-18-8 is a positive allosteric modulator (PAM) of calcimimetic calcium-sensing receptor (CaSR) with an EC50 of 132 nM.	price>
R-R-2652	AC-265347 CAS No.1253901-26-6	AC-265347/CAS No.1253901-26-6 is a calcium-sensing receptor (CaSR) agonist and positive allosteric modulator (ago-PAM) with the functional affinity (pKB) of 5.1. AC-265347 can be used for the research of hyperparathyroidism and related diseases.	price>
R-R-2653	L-Glutamine-13C5 CAS No.184161-19-1	L-Glutamine-13C5/CAS No.184161-19-1 is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.	price>
R-R-2654	LY341495 CAS No.201943-63-7	LY341495/CAS No.201943-63-7 is a metabotropic glutamate receptor (mGluR) antagonist with IC50s of 21 nM, 14 nM, 7.8 μM, 8.2 μM, 170 nM, 990 nM, 22 μM for mGlu2, mGlu3, mGlu1a, mGlu5a, mGlu8, mGlu7, and mGlu4 receptors, respectively.	price>
R-R-2655	Ro 67-7476 CAS No.298690-60-5	Ro 67-7476/CAS No.298690-60-5 is a potent positive allosteric modulator of mGluR1 and potentiates glutamate-induced calcium release in HEK293 cells expressing rat mGluR1a with an EC50 of 60.1 nM. Ro 67-7476 is a potent P-ERK1/2 agonist and activates ERK1/2 phosphorylation in the absence of exogenously added glutamate (EC50=163.3 nM).	price>
R-R-2656	Eglumegad hydrochloride	Eglumegad (LY354740) hydrochloride is a highly potent and selective group II (mGlu2/3) receptor agonist with IC50s of 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively. Eglumegad hydrochloride protects neurons from NMDA toxicity. Eglumegad hydrochloride has anxiolytic- and antipsychotic-like effects.	price>
R-R-2657	MPEP Hydrochloride CAS No.219911-35-0	MPEP Hydrochloride/CAS No.219911-35-0 is a potent, selective, noncompetitive, orally active and systemically active mGlu5 receptor antagonist, with an IC50 of 36 nM for completely inhibiting quisqualate-stimulated phosphoinositide (PI) hydrolysis. MPEP Hydrochloride has anxiolytic-or antidepressant-like effects. MPEP (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>

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