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Home > products > apis> gpcr-g-protein
Catalog name Description price
R-R-4207 CCR4 antagonist 4 CAS No.668980-17-4 CCR4 antagonist 4 (compound 22)/CAS No.668980-17-4 is a selective and potent antagonist of the CC chemokine receptor-4 (CCR4), with an IC50 of 0.02 μM. CCR4 antagonist 4 also blocks MDC-mediated chemotaxis (IC50: 0.007 μM) and Ca2+ mobilization (IC50: 0.003 μM). CCR4 antagonist 4 can be used for allergic inflammation research. price>
R-R-4208 Nifeviroc CAS No.934740-33-7 Nifeviroc/CAS No.934740-33-7 is an orally active CCR5 antagonist. Nifeviroc is used for the study of HIV type-1 infection. price>
R-R-4209 CCR2 antagonist 4 CAS No.226226-39-7 CCR2 antagonist 4 (Teijin compound 1)/CAS No.226226-39-7 is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM. price>
R-R-4210 Aplaviroc hydrochloride CAS No.461023-63-2 Aplaviroc (AK 602) hydrochloride/CAS No.461023-63-2, a SDP derivative, is a CCR5 antagonist, with IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW. price>
R-R-4211 AZD-1678 CAS No.942137-41-9 AZD-1678/CAS No.942137-41-9 is a potent CCR4 receptor antagonist, with a pIC50 of 8.6. price>
R-R-4212 CCR4 antagonist 3 CAS No.1957-01-3 CCR4 antagonist 3/CAS No.1957-01-3 is a potent chemokine receptor 4 (CCR4) antagonist with an IC50 value of 1.7 μM for [125I]TARC (thymus and activation regulated chemokine). CCR4 antagonist 3 inhibits binding of radiolabeled TARC and macrophage-derived chemokine (MDC) to CCR4 receptors on the surface of CEM cells. CCR4 antagonist 3 also inhibits the in vitro migration of CEM cells mediated by TARC (IC50 = 6.4 μM). price>
R-R-4213 CCX354 CAS No.1010073-75-2 CCX354/CAS No.1010073-75-2 is an antagonist of CCR1, with anti-inflammatory activity. price>
R-R-4214 CCR4-351 hydrochloride CAS No.2174938-71-5 CCR4-351 hydrochloride/CAS No.2174938-71-5 is an orally active, potent and selective CCR4 antagonist. CCR4-351 hydrochloride, featuring a novel piperidinyl-azetidine motif, has IC50s of 22 nM and 50 nM in the calcium flux and CTX assay. CCR4-351 hydrochloride has antitumor activity. price>
R-R-4215 INCB3344 R-isomer INCB3344 R-isomer is the R-isomer of INCB3344. INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity. price>
R-R-4216 BMS-817399 CAS No.1202400-18-7 BMS-817399/CAS No.1202400-18-7 is a potent, selective, and orally bioavailable CCR1 antagonist. BMS-817399 exhibits CCR1 binding affinity and chemotaxis inhibition potencies of 1 and 6 nM (IC50), respectively. BMS-817399 can be used for the research of rheumatoid arthritis. price>