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Home > products > apis> gpcr-g-protein
Catalog name Description price
R-R-4098 Tedalinab CAS No.916591-01-0 Tedalinab (GRC-10693)/CAS No.916591-01-0 is a potent, orally active, and selective cannabinoid receptor 2 (CB2) agonist. Tedalinab has >4700-fold functional selectivity for CB2 over CB1. Tedalinab has potential for neuropathic pain and osteoarthritis treatment. price>
R-R-4099 Pregnenolone-d4-1 CAS No.61574-54-7 Pregnenolone-d4-1/CAS No.61574-54-7 is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels. price>
R-R-4100 GAT211 CAS No.102704-40-5 GAT211/CAS No.102704-40-5 is a cannabinoid 1 receptor (CB1R) positive allosteric modulator (PAM). GAT211 activates cAMP and β-arrestin2 with EC50 values of 260 nM and 650 nM, respectively. GAT211 inhibits GAT211 can be used for neuropathic and/or inflammatory pain research. price>
R-R-4101 CB2R PAM CAS No.2244579-87-9 CB2R PAM/CAS No.2244579-87-9 is an orally active cannabinoid type-2 receptors (CB2Rs) positive allosteric modulator. CB2R PAM displays antinociceptive activity in vivo in an experimental mouse model of neuropathic pain. price>
R-R-4102 CB1 agonist 1 CAS No.851212-80-1 CB1 agonist 1 (compound 22)/CAS No.851212-80-1 is an agonist of CB1. CB1 agonist 1 shows affinity to CB1 receptor with an pIC50 value of 5.7. CB1 agonist 1 can be used for the research of brain disorders. price>
R-C-2403 Atipamezole CAS:104054-27-5 Atipamezole(MPV-1248,MPV1248,Antisedan)is a synthetic α2 adrenergic receptor antagonist.It has also been researched in humans as a potential anti-Parkinsonian drug. price>
R-R-4103 Taranabant racemate CAS No.701977-00-6 Taranabant racemate (MK-0364 racemate)/CAS No.701977-00-6 is an antagonist and/or inverse agonist of the Cannabinoid-1 (CB1) receptor extracted from patent WO 2004048317 A1. price>
R-R-4104 SCH 336 CAS No.447459-51-0 SCH 336/CAS No.447459-51-0 is a potent, selective, inverse and orally active CB2 agonist. SCH 336 inhibits BaF3/CB2 migration. SCH 336 significantly inhibits the migration of leukocytes in vivo. SCH 336 blocks ovalbumin-induced lung eosinophilia in mice. price>
R-R-4105 Tetrahydromagnolol CAS No.20601-85-8 Tetrahydromagnolol (Magnolignan)/CAS No.20601-85-8, a main metabolite of Magnolol, is a potent and selective cannabinoid CB2 receptor agonist with an EC50 of 170 nM and a Ki of 416 nM. Tetrahydromagnolol possesses 20-fold more selective for CB2 receptor than CB1 receptor. Tetrahydromagnolol is also a weak GPR55 receptor antagonist. price>
R-R-4106 AZD1940 CAS No.881413-29-2 AZD1940/CAS No.881413-29-2 is an orally active, high affinity cannabinoid CB1/CB2 receptor agonist with pKi values of 7.93 and 9.06 for human CB1R and CB2R, respectively. AZD1940 shows a robust analgesia action. price>