Product apis-dna-damage-dna-repa

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Catalog	name	Description	price
R-R-4800	Uridine 3,5-diphosphate CAS No.2922-95-4	Uridine 3,5-diphosphate (3,5-UDP; Compound pUp)/CAS No.2922-95-4 is a competitive RNase inhibitor.	price>
R-R-4801	Halofuginone hydrochloride CAS No.1217623-74-9	Halofuginone (RU-19110) hydrobromid/CAS No.1217623-74-9, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone hydrobromid is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone hydrobromid has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects.	price>
R-R-4802	Folic acid-d4 CAS No.171777-72-3	Folic acid-d4/CAS No.171777-72-3 is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.	price>
R-R-4803	5-BrdUTP sodium salt CAS No.102212-99-7	5-BrdUTP sodium salt/CAS No.102212-99-7 is a TdT substrate which can be used to label the DNA double-strand breaks.	price>
R-R-4805	DHODH-IN-8 CAS No.1148126-03-7	DHODH-IN-8 (Compound 27)/CAS No.1148126-03-7 is an inhibitor of human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) with IC50s of 0.13 μM and 47.4 μM, and Kis of 0.016 μM and 5.6 μM, respectively. DHODH-IN-8 has antimalarial activity.	price>
R-R-4807	Tanespimycin CAS No.75747-14-7	Tanespimycin (17-AAG)/CAS No.75747-14-7 is a potent HSP90 inhibitor with an IC50 of 5 nM, having 100-fold higher binding affinity for tumor cell-derived HSP90 than normal cell-derived HSP90. Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates stk38 gene expression.	price>
R-R-4808	Geldanamycin CAS No.30562-34-6	Geldanamycin/CAS No.30562-34-6 is a Hsp90 inhibitor with antimicrobial activity against many Gram-positive and some Gram-negative bacteria. Geldanamycin has anti-influenza virus H5N1 activities.	price>
R-R-4809	HA15 CAS No.1609402-14-3	HA15/CAS No.1609402-14-3 is a potent and specific inhibitor of ER chaperone BiP/GRP78/HSPA5, inhibits the ATPase activity of BiP, with anti-cancerous activity.	price>
R-R-4810	Gamitrinib TPP hexafluorophosphate CAS No.1131626-47-5	Gamitrinib TPP hexafluorophosphate/CAS No.1131626-47-5 is a Gamitrinib (GA) mitochondrial matrix inhibitor. Gamitrinib TPP hexafluorophosphate is a mitochondrial targeted HSP90 inhibitor with anti-cancer activity.	price>
R-R-4811	Alvespimycin hydrochloride CAS No.467214-21-7	Alvespimycin hydrochloride (17-DMAG hydrochloride; KOS-1022; BMS 826476)/CAS No.467214-21-7 is a potent inhibitor of Hsp90, binding to Hsp90 with EC50 of 62±29 nM.	price>

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