Product apis-dna-damage-dna-repa

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Catalog	name	Description	price
R-R-4810	Gamitrinib TPP hexafluorophosphate CAS No.1131626-47-5	Gamitrinib TPP hexafluorophosphate/CAS No.1131626-47-5 is a Gamitrinib (GA) mitochondrial matrix inhibitor. Gamitrinib TPP hexafluorophosphate is a mitochondrial targeted HSP90 inhibitor with anti-cancer activity.	price>
R-R-4811	Alvespimycin hydrochloride CAS No.467214-21-7	Alvespimycin hydrochloride (17-DMAG hydrochloride; KOS-1022; BMS 826476)/CAS No.467214-21-7 is a potent inhibitor of Hsp90, binding to Hsp90 with EC50 of 62±29 nM.	price>
R-R-4832	Viltolarsen sodium	Viltolarsen (NS-065/NCNP-01) sodium is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen sodium binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen sodium has the potential for Duchenne muscular dystrophy (DMD) research.	price>
R-R-4833	DMTr-5-fluoro-2-deoxycytidine-phosphoramidite CAS No.143774-48-5	DMTr-5-fluoro-2-deoxycytidine-phosphoramidite (compound 1B)/CAS No.143774-48-5 is a phosphoramidite of 5-Fluoro-2-deoxycytidine.	price>
R-R-4834	Trifluridine/tipiracil hydrochloride mixture CAS No.733030-01-8	Trifluridine/tipiracil hydrochloride mixture (TAS-102)/CAS No.733030-01-8 is a potent and orally active nucleoside antitumor agent. The composition of Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a 1:0.5 mixture (on a molar basis) of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI). Trifluridine/tipiracil hydrochloride mixture (TAS-102) shows the antitumor activity mainly via the inhibition of thymidylate synthase (TS) and incorporation into DNA.	price>
R-R-4835	2-Chloroadenosine CAS No.146-77-0	2-Chloroadenosine/CAS No.146-77-0, a stable adenosine analogue, protects against long term development of ischaemic cell loss in the rat hippocampus. 2-Chloroadenosine is an apparent competitive inhibitor of uridine influx (apparent Ki=33 μM) and high-affinity nitrobenzylthioinosine binding (apparent Ki=0.18 mM). 2-Chloroadenosine is a transported permeant for the nucleoside transporter in human erythrocytes.	price>
R-R-4836	7-Methylguanosine CAS No.20244-86-4	7-Methylguanosine/CAS No.20244-86-4 is a novel cNIIIB nucleotidase inhibitor with IC50 value of 87.8 ± 7.5 µM.	price>
R-R-4837	Sangivamycin CAS No.18417-89-5	Sangivamycin (NSC 65346)/CAS No.18417-89-5, a nucleoside analog, is a potent inhibitor of protein kinase C (PKC) with an Ki of 10 μM. Sangivamycin has potent antiproliferative activity against a variety of human cancers.	price>
R-R-4838	3-Methylcytidine CAS No.2140-64-9	3-Methylcytidine/CAS No.2140-64-9, a urinary nucleoside, can be used as a biomarker of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.	price>
R-R-4839	6-Thioinosine CAS No.574-25-4	6-Thioinosine (6TI)/CAS No.574-25-4 is a purine antimetabolite, acts as an anti-adipogenesis agent, downregulates mRNA levels of PPAR γ and C/EBPα, as well as PPAR γ target protein such as LPL, CD36, aP2, and LXRα.	price>

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