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Halofuginone hydrochloride CAS No.1217623-74-9
Halofuginone hydrochloride CAS No.1217623-74-9
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-4801 | 1mg | 500.00 | + Add to cart |
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| R-R-4801 | 2mg | 820.00 | + Add to cart |
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Product description
Halofuginone (RU-19110) hydrobromid/CAS No.1217623-74-9, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone hydrobromid is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone hydrobromid has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects.
| Appearance | N/A |
|---|---|
| Molecular Weight | 451.14 |
| Purity | >90% |
| CAS | 1217623-74-9 |
| Formula | C16H18BrCl2N3O3 |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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