Product apis-dna-damage-dna-repa

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Catalog	name	Description	price
R-R-4644	Dithranol CAS No.1143-38-0	Dithranol (Anthralin)/CAS No.1143-38-0 is an anthraquinone derivative, with potent anti-psoriatic effects. Dithranol can inhibit DNA replication and repair.	price>
R-R-4645	Ethynylcytidine CAS No.180300-43-0	Ethynylcytidine (ECyD)/CAS No.180300-43-0, a nucleoside analog and a potent inhibitor of RNA synthesis, inhibits RNA polymerases I, II and II. Ethynylcytidine has robust antitumor activity in a wide range of models of cancer. Ethynylcytidine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.	price>
R-R-4646	TTP-8307 CAS No.950225-08-8	TTP-8307/CAS No.950225-08-8 is a potent inhibitor of the replication of several rhino- and enteroviruses. TTP-8307 inhibits coxsackievirus B3 (CVB3; EC50=1.2 μM) and poliovirus by interfering with the synthesis of viral RNA. TTP-8307 exerts antiviral activity through oxysterol-binding protein (OSBP).	price>
R-R-4647	Neobavaisoflavone CAS No.41060-15-5	Neobavaisoflavone/CAS No.41060-15-5, a flavonoid, is isolated from the seeds of Psoralea corylifolia. Neobavaisoflavone exhibits anti-inflammatory, anti-cancer and anti-oxidation activities. Neobavaisoflavone inhibits DNA polymerase at moderate to high concentrations. Neobavaisoflavone also inhibits platelet aggregation.	price>
R-R-4648	BRD32048 CAS No.433694-46-3	BRD32048/CAS No.433694-46-3 is a direct binder of ETV1 with a KD of 17.1 μM. BRD32048 modulates both ETV1-mediated transcriptional activity and invasion of ETV1-driven cancer cells. BRD32048 inhibits ETV1 acetylation and promotes its degradation. BRD32048 acts as a top candidate ETV1 perturbagen.	price>
R-R-4649	Cinoxacin CAS No.28657-80-9	Cinoxacin (Compound 64716)/CAS No.28657-80-9, a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis.	price>
R-R-4650	Deoxyguanosine triphosphate trisodium salt CAS No.93919-41-6	Deoxyguanosine triphosphate (dGTP) trisodium salt/CAS No.93919-41-6 is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification.	price>
R-R-4651	Braco-19 trihydrochloride CAS No.1177798-88-7	Braco-19 trihydrochloride/CAS No.1177798-88-7 is a potent telomerase/telomere inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor.	price>
R-R-4652	NVS-SM2 CAS No.1562333-92-9	NVS-SM2/CAS No.1562333-92-9 is a potent, orally active and brain-penetrant SMN2 splicing enhancer with an EC50 of 2 nM for SMN. NVS-SM2 enhances U1-pre-mRNA association. NVS-SM2 promotes exon 7 inclusion and restores normal survival motor neuron (SMN) protein expression. NVS-SM2 can be used for spinal muscular atrophy (SMA) research.	price>
R-R-4653	ERCC1-XPF-IN-2 CAS No.1808986-37-9	ERCC1-XPF-IN-2/CAS No.1808986-37-9 is a potent ERCC1-XPF endonuclease inhibitor with an IC50 value of 0.6 µM. ERCC1-XPF-IN-2 shows activity in nucleotide excision repair, cisplatin enhancement and γH2AX assays.	price>

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