Product apis-apoptosis

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Catalog	name	Description	price
R-C-2610	YM155 (Sepantronium Bromide) CAS:781661-94-7	YM155(Sepantronium Bromide)is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54nM in HeLa-SURP-luc and CHO-SV40-luc cells;does not significantly inhibit SV40 promoter activity,but is observed to slightly inhibit the interaction of Survivin with XIAP.	price>
R-C-2644	Z-DEVD-FMK CAS:210344-95-9	Z-DEVD-FMK(Caspase-3 Inhibitor)is a specific,irreversible Caspase-3 inhibitor,and also shows potent inhibition on caspase-6,caspase-7,caspase-8, and caspase-10.	price>
R-C-2645	Z-IETD-FMK CAS:210344-98-2	Z-IETD-FMK(Z-IE(OMe)TD(OMe)-FMK)is a selective and cell permeable caspase-8 inhibitor.Z-IETD-FMK is also a granzyme B inhibitor.	price>
R-C-2646	Z-WEHD-FMK CAS:210345-00-9	Z-WEHD-FMK is a potent,cell-permeable and irreversible caspase-1/5 inhibitor.Z-WEHD-FMK also exhibits a robust inhibitory effect on cathepsin B activity (IC50=6μM).Z-WEHD-FMK can be used to investigate cells for evidence of apoptosis.	price>
R-C-2647	Ac-LEHD-AFC	Ac-LEHD-AFC,fluorogenic caspase substrate.Analog of the caspase-9 substrate, LEHD-AFC.	price>
R-C-2648	Gambogic acid CAS:2752-65-0	Gambogic Acid(Beta-Guttiferrin)is derived from the gamboges resin of the tree Garcinia hanburyi.Gambogic Acid (Beta-Guttiferrin)inhibits Bcl-XL,Bcl-2,Bcl-W,Bcl-B,Bfl-1 and Mcl-1 with IC50s of 1.47μM,1.21μM,2.02 μM,0.66μM,1.06μM and 0.79μM.	price>
R-C-2650	Necrostatin-1 CAS:4311-88-0	Necrostatin-1(Nec-1)is a specific RIP1(RIPK1)inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM in 293T cells.Necrostatin-1 also blocks IDO and suppresses autophagy and apoptosis.	price>
R-C-2651	Pifithrin-β CAS:60477-34-1	Pifithrin-β(PFT β)is a potent p53 inhibitor with an IC50 of 23μM.	price>
R-C-2657	Dp44mT CAS: 152095-12-0	Dp44mT is an iron chelator,possessing DNA-damaging activity mediated by top2a inhibition.	price>
R-C-2567	Z-YVAD-FMK CAS:210344-97-1	Z-YVAD-FMK is a cell-permeable caspase-1 and -4 inhibitor with anti-inflammatory and anti-tumor activities.	price>

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