Product apis-apoptosis

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Catalog	name	Description	price
R-C-2600	NSC 66811 CAS:6964-62-1	NSC 66811 is a MDM2-p53 inhibitor,with a Ki of 120nM for binding to MDM2.	price>
R-C-2601	Mcl1-IN-1 CAS:713492-66-1	Mcl1-IN-1 is a potent and selective inhibitor of the apoptosis regulating proteins Mcl-1.	price>
R-C-2602	NSC 319726 CAS:71555-25-4	NSC319726(ZMC1)is a mutant p53R175 reactivator;inhibits growth of fibroblasts expressing the p53R175 mutation(IC50=8nM);shows no inhibition for p53 wild-type cells.	price>
R-C-2603	MIRA-1NSC19630 CAS:72835-26-8	MIRA-1 restores wild-type conformation,function and DNA binding activity to mutant p53.Induces p53 transcriptional transactivation of p21,MDM2 and PUMA.	price>
R-C-2604	Brassinolide CAS:72962-43-7	Brassinolide,a plant steroid isolated from Brassica napus pollen,promotes cell elongation and cell devision and thus regulates plant growth and development.	price>
R-C-2605	Ivachtin CAS:745046-84-8	Ivachtin(Caspase-3 Inhibitor VII;compound 7a)is a nonpeptide,noncompetitive and reversibl caspase-3 inhibitor with an IC50 of 23nM.Ivachtin has modest selectivity for the remaining caspases.	price>
R-C-2606	Epibrassinolide CAS:78821-43-9	Epibrassinolide(24-Epibrassinolide)is a ubiquitously occurring plant growth hormone which shows great potential to alleviate heavy metals and pesticide stress in plants.Epibrassinolide is a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth.	price>
R-C-2607	Roquinimex CAS:84088-42-6	Roquinimex(Linomide;PNU212616;ABR212616)is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF alpha.	price>
R-C-2608	Necrostatin 2 CAS:852391-19-6	Necrostatin 2(Nec-2)is a novel and potent necroptosis inhibitor with EC50 of 50 nM.It is an analog of necrostatin 1(nec-1).Necroptosis is a mechanism of necrotic cell death induced by apoptotic stimuli in the form of death domain receptor engagement by their respective ligands under conditions where apoptotic execution is prevented.	price>
R-C-2609	TLQP 21 CAS:869988-94-3	TLQP-21,a VGF-derived peptide endowed of endocrine and extraendocrine properties,is a potent G-protein-coupled receptor complement-3a receptor 1(C3aR1)agonist(EC50:mouse TLQP-21=10.3μM;human TLQP-21=68.8μM).TLQP-21 activates C3aR1 to induce an increase of intracellular Ca2+.TLQP-21 is used for the research in regulation of nociception and other relevant physiologic functions.	price>

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