Product apis-apoptosis

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Catalog	name	Description	price
R-R-2107	Quinacrine dihydrochloride CAS No.69-05-6	Quinacrine (Mepacrine) dihydrochloride/CAS No.69-05-6 is an orally bioavailable antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine dihydrochloride suppresses NF-κB and activate p53 signaling, which results in the induction of the apoptosis.	price>
R-R-2108	Betamethasone CAS No.378-44-9	Betamethasone/CAS No.378-44-9 is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities. Betamethasone accelerates fetal lung maturation and induces gene expression and apoptosis.	price>
R-R-2109	Physalin A CAS No.23027-91-0	Physalin A/CAS No.23027-91-0 is a withanolide isolated from Physalis alkekengi var. franchetii. Physalin A induces apoptosis associated with up-regulation of caspase-3 and caspase-8 expression. Physalin A induces autophagy, found to antagonize apoptosis in HT1080 cells. Physalin A has the potential for the research of cancer disease.	price>
R-R-2110	ACBI1 CAS No.2375564-55-7	ACBI1/CAS No.2375564-55-7 is a potent and cooperative SMARCA2, SMARCA4 and PBRM1 degrader with DC50s of 6, 11 and 32 nM, respectively. ACBI1 is a PROTAC degrader. ACBI1 shows anti-proliferative activity. ACBI1 induces apoptosis.	price>
R-R-2111	API-1 CAS No.36707-00-3	API-1/CAS No.36707-00-3, a potent Akt/PKB inhibitor, binds to the PH domain and inhibits Akt membrane translocation. API-1 efficiently reduces the phosphorylation levels of Akt with an IC50 of ∼0.8 μM. API-1 is selective for PKB and does not inhibit the activation of PKC, and PKA. API-1 also induces apoptosis by synergizing with TNF-related apoptosis-inducing ligand (TRAIL).	price>
R-R-2112	DMU-212 CAS No.134029-62-2	DMU-212/CAS No.134029-62-2 is a methylated derivative of Resveratrol (HY-16561), with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. DMU-212 induces mitotic arrest via induction of apoptosis and activation of ERK1/2 protein. DMU-212 has orally active.	price>
R-R-2113	Brazilein CAS No.600-76-0	Brazilein/CAS No.600-76-0 is an important immunosuppressive component isolated from Caesalpinia sappan L. Brazilein induces apoptosis in mice spleen lymphocytes.	price>
R-R-2114	ASR-488 CAS No.2690312-65-1	ASR-488/CAS No.2690312-65-1 activates the mRNA-binding protein CPEB1, induces apoptosis and inhibits bladder cancer growth.	price>
R-R-2115	Kumatakenin CAS No.3301-49-3	Kumatakenin/CAS No.3301-49-3, a flavonoid that is isolated from cloves shows the effect of inducing apoptosis in ovarian cancer cells.	price>
R-R-2116	Paederosidic acid CAS No.18842-98-3	Paederosidic acid/CAS No.18842-98-3 is isolated from P. scandens with anticancer and anti‐inflammation activities. Paederosidic acid inhibits lung caner cells via inducing mitochondria-mediated apoptosis.	price>

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