Product apis-apoptosis

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Catalog	name	Description	price
R-R-2087	Nauclefine CAS No.57103-51-2	Nauclefine/CAS No.57103-51-2 is an indole alkaloid isolated from Nauclea officinalis. Nauclefine acts as a PDE3A modulator to induce cancer cell apoptosis through a PDE3A-SLFN12-dependent death pathway.	price>
R-R-2088	HP590	HP590 is an orally active, novel and potent STAT3 inhibitor (STAT3 luciferase activity: IC50=27.8 nM; ATP inhibition: IC50=24.7 nM). HP590 shows anti-proliferative activity to gastric cancer cells and induces apoptosis.	price>
R-R-2089	Terrein CAS No.582-46-7	Terrein/CAS No.582-46-7 is a melanogenesis inhibitor. Terrein induces apoptosis in breast cancer cell lines . Terrein is an inhibitor of quorum sensing and c-di-GMP in Pseudomonas aeruginosa.	price>
R-R-2090	MMP2-IN-1 CAS No.2764598-01-6	MMP2-IN-1/CAS No.2764598-01-6 is a moderate potenet MMP2 inhibitor with IC50 of 6.8 µM. MMP2-IN-1 exhibits remarkable antiproliferative activity in certain cancer cells by arresting the cell cycle and inducing apoptosis.	price>
R-R-2091	Damulin B CAS No.1202868-75-4	Damulin B/CAS No.1202868-75-4 is a dammarane-type saponin found in Gynostemma pentaphyllum.Damulin B can induce cell apoptosis and has anti-cancer activities in vitro.	price>
R-R-2092	Polyphyllin VI CAS No.55916-51-3	Polyphyllin VI/CAS No.55916-51-3, an active saponin, possess anti-cancer activities. Polyphyllin VI induces G2/M cell cycle arrest and triggers apoptosis. Polyphyllin VI induces caspase-1-mediated pyroptosis via the induction of ROS/NF-κB/NLRP3/GSDMD signal axis in non-small cell lung cancer.	price>
R-R-2093	Rohinitib CAS No.1139253-73-8	Rohinitib/CAS No.1139253-73-8 is a potent and specific eIF4A inhibitor. Rohinitib induces cell apoptosis of acute myeloid leukemia (AML) cell lines and reduces the leukemia burden of AML xenograft model. Rohinitib can be used for the research of AML.	price>
R-R-2094	Pinosylvin CAS No.22139-77-1	Pinosylvin/CAS No.22139-77-1 is a pre-infectious stilbenoid toxin isolated from the heartwood of Pinus species, has anti-bacterial activities. Pinosylvin is a resveratrol analogue, can induce cell apoptosis and autophapy in leukemia cells.	price>
R-R-2095	Bleomycin A5 CAS No.11116-32-8	Bleomycin A5 (Pingyangmycin)/CAS No.11116-32-8 is an orally active glycopeptide antibiotics. Bleomycin A5 has a role as an antineoplastic agent, an apoptosis inducer and a bacterial metabolite.	price>
R-R-2096	NSC 107512 CAS No.22242-89-3	NSC 107512/CAS No.22242-89-3 is a potent inhibitor of cyclin-dependent kinase 9 (CDK9). NSC 107512 is a class of sangivamycin-like molecules (SLM). NSC 107512 inhibits growth and induces apoptosis of multiple myeloma tumors.	price>

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