Product apis-apoptosis

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Catalog	name	Description	price
R-R-2067	Tauroursodeoxycholate CAS No.14605-22-2	Tauroursodeoxycholate (Tauroursodeoxycholic acid)/CAS No.14605-22-2 is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.	price>
R-R-2068	Enpp/Carbonic anhydrase-IN-1 CAS No.2883495-35-8	Enpp/Carbonic anhydrase-IN-1 (compound 1e)/CAS No.2883495-35-8 is a potent Enpp and carbonic anhydrase inhibitor with IC50s of 1.36, 1.35, 3.00, 0.88, 1.02 μM for NPP1, NPP2, NPP3, CA-II, CA-IX respectively. Enpp/Carbonic anhydrase-IN-1 shows antiproliferative activity for cancer cells and low cytotoxic against normal cells. Enpp/Carbonic anhydrase-IN-1 induces Apoptosis.	price>
R-R-2069	Enpp/Carbonic anhydrase-IN-2 CAS No.2883495-39-2	Enpp/Carbonic anhydrase-IN-2 (compound 1i)/CAS No.2883495-39-2 is a potent Enpp and carbonic anhydrase inhibitor with IC50s of 1.13, 1.07, 0.74, 0.33, 0.68 for NPP1, NPP2, NPP3, CA-IX, CA-XII respectively. Enpp/Carbonic anhydrase-IN-2 shows antiproliferative activity for cancer cells and low cytotoxic against normal cells. Enpp/Carbonic anhydrase-IN-2 induces Apoptosis.	price>
R-R-2070	Aminoguanidine hydrochloride CAS No.1937-19-5	Aminoguanidine hydrochloride (Pimagedine hydrochloride)/CAS No.1937-19-5 is an inhibitor of diamine oxidase and nitric oxide synthase. Aminoguanidine hydrochloride has a dose-dependent inhibitory effect on apoptosis induced by Doxorubicin (HY-15142). Aminoguanidine hydrochloride has antioxidant properties. Aminoguanidine hydrochloride can be used in diabetic nephropathy research.	price>
R-R-2071	(20S)-Protopanaxadiol CAS No.30636-90-9	20S-protopanaxadiol (aPPD)/CAS No.30636-90-9 is a metabolite of ginseng saponins, inhibits Akt activity and induces apoptosis in various tumor cells.	price>
R-R-2072	(Rac)-Indoximod CAS No.26988-72-7	(Rac)-Indoximod (1-Methyl-DL-tryptophan)/CAS No.26988-72-7 is an indoleamine 2,3-dioxygenase (IDO) inhibitor. Co-treatment with IFN-γ and (Rac)-Indoximod markedly reduces the activity of human cardiac myofibroblasts (hCMs) expressing α-SMA and induces apoptosis through up-regulating the IRF-1, Fas, and FasL genes.	price>
R-R-2073	N-Oleoyl-L-serine CAS No.107743-37-3	N-Oleoyl-L-Serine/CAS No.107743-37-3 is an endogenous amide of long-chain fatty acids with ethanolamine (N-acyl amides). N-Oleoyl-L-Serine is a lipid regulator of bone remodeling and stimulates osteoclast apoptosis. N-Oleoyl-L-Serine can be used for antiosteoporotic drug discovery development.	price>
R-R-2074	NSC 146109 hydrochloride CAS No.59474-01-0	NSC 146109 hydrochloride/CAS No.59474-01-0 is a small-molecule p53 activator that target MDMX and can be used for breast cancer research. NSC 146109 hydrochloride is a pseudourea derivative, promotes breast cancer cells to undergo apoptosis through activating p53 and inducing expression of proapoptotic genes.	price>
R-R-2075	CWI1-2 CAS No.2408590-36-1	CWI1-2/CAS No.2408590-36-1 is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and shows promising anti-leukemic effects.	price>
R-R-2076	Maytansinol CAS No.57103-68-1	Maytansinol (Ansamitocin P-0)/CAS No.57103-68-1 is a derivative of Maytansine. Maytansinol can inhibit tubulin polymerization and induce apoptosis. Maytansinol has antitumor activity. Maytansinol can be used in cancer drug research.	price>

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