Product apis-apoptosis

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Catalog	name	Description	price
R-R-2047	Tauroursodeoxycholate dihydrate CAS No.117609-50-4	Tauroursodeoxycholate (Tauroursodeoxycholic acid; TDUCA) dihydrate/CAS No.117609-50-4 is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.	price>
R-R-2048	Toddaculin CAS No.4335-12-0	Toddaculin/CAS No.4335-12-0 is a natural coumarin that can induce differentiation and apoptosis in leukemic cells. Toddaculin suppresses excess osteoclast activity and enhances osteoblast differentiation and mineralization. Toddaculin also exhibits anti-inflammatory activity.	price>
R-R-2049	L-Asparaginase CAS No.9015-68-3	L-Asparaginase (L-ASNase)/CAS No.9015-68-3 is a deamidating enzyme that catalyses the hydrolysis of L-asparagine and L-glutamine, and can be used for the research of acute lymphoblastic leukemia. L-Asparaginase depletes L-asparagine from plasma resulting in inhibition of RNA and DNA synthesis with the subsequent blastic cell apoptosis.	price>
R-R-2050	STL127705 CAS No.1326852-06-5	STL127705 (Compound L)/CAS No.1326852-06-5 is a potent Ku 70/80 heterodimer protein inhibitor with an IC50 of 3.5 μM. STL127705 interferes the binding of Ku70/80 to DNA and by inhibits the activation of the DNA-PKCS kinase. STL127705 shows antiproliferative and anticancer activity. STL127705 induces apoptosis.	price>
R-R-2051	Fasnall CAS No.929978-58-5	Fasnall/CAS No.929978-58-5 is a selective fatty acid synthase (FASN) inhibitor with an IC50 of 3.71 μM. Fasnall induces apoptosis in HER2+ breast cancer cell lines. Fasnall shows potent anti-tumor activities.	price>
R-R-2052	PETCM CAS No.10129-56-3	PETCM/CAS No.10129-56-3 is an activator of caspase-3 and acts as an cytochrome c (cyto c)-dependent manner. PETCM promotes Apaf-1 oligomerization and induces cell apoptosis in HeLa cells.	price>
R-R-2053	Chamaejasmine CAS No.69618-96-8	Chamaejasmine/CAS No.69618-96-8 is a biflavonoid that can be isolated from the roots of Stellera chamaejasme L. Chamaejasmine has antitumor activity. Chamaejasmine induces cell apoptosis, autophagy and ROS production, and activates the activity of AMPK/mTOR signal pathway.	price>
R-R-2054	(E)-[6]-Dehydroparadol CAS No.878006-06-5	(E)-[6]-Dehydroparadol/CAS No.878006-06-5, an oxidative metabolite of [6]-Shogaol (HY-14616), is a potent Nrf2 activator. (E)-[6]-Dehydroparadol can inhibit the growth and induce the apoptosis of human cancer cells.	price>
R-R-2055	HX630 CAS No.188844-52-2	HX630/CAS 188644-52-2 is a potent retinoic acid X receptor (RXR) agonist that can induce apoptosis and has anti-tumor effects.	price>
R-R-2056	L-threo-Sphingosine CAS No.25695-95-8	L-threo-Sphingosine/CAS No.25695-95-8 is a potent MAPK inhibitor. L-threo-Sphingosine induces apoptosis and clear DNA fragmentation. L-threo-Sphingosine shows anticancer effect.	price>

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