Product apis-apoptosis

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Catalog	name	Description	price
R-R-2077	Cycleanine CAS No.518-94-5	Cycleanine/CAS No.518-94-5 is a potent vascular selective Calcium antagonist. Cycleanine has analgesic, muscle relaxant and anti-inflammatory activities. Cycleanine has potential for anti-ovarian cancer acting through the apoptosis pathway.	price>
R-R-2078	Telekin CAS No.6752-90-5	Telekin/CAS No.6752-90-5 is an eucalyptus-type sesquiterpene lactone compound found in Carpesium divaricatum. Telekin can activate mitochondria-mediated cell apoptosis and has anticancer activity.	price>
R-R-2079	Polyporenic acid C CAS No.465-18-9	Polyporenic acid C/CAS No.465-18-9 is a lanostane-type triterpenoid isolated from P. cocos. Polyporenic acid C induces cell apoptosis through the death receptor-mediated apoptotic pathway without the involvement of the mitochondria. Polyporenic acid C is promising agent for lung cancer therapy.	price>
R-R-2080	HDAC/JAK/BRD4-IN-1 CAS No.2755325-84-7	HDAC/JAK/BRD4-IN-1(compound 25ap)/CAS No.2755325-84-7 is a potent HDAC/JAK/BRD4 triple inhibitor. HDAC/JAK/BRD4-IN-1 inhibit cell growth and induces apoptosis in MDA-MB-231 cells, and shows anticancer activity in vivo.	price>
R-R-2081	Cyasterone CAS No.17086-76-9	Cyasterone/CAS No.17086-76-9, a natural EGFR inhibitor, mainly isolated from Ajuga decumbens Thunb (Labiatae). Cyasterone manifests anti-proliferation effect by induced apoptosis and cell cycle arrests. Cyasterone may serves as a therapeutic anti-tumor agent against human tumors.	price>
R-R-2082	Glychionide A CAS No.119152-50-0	Glychionide A/CAS No.119152-50-0 is a flavonoside that can be found in the roots of Glychirriza glabra. Glychionide A promotes apoptosis and autophagy of PANC-1 pancreatic cancer cells. Glychionide A can be used for the research of cancer.	price>
R-R-2083	ADT-OH CAS No.18274-81-2	ADT-OH/CAS No.18274-81-2 is a hydrogen sulfide-releasing donor. ADT-OH induces apoptosis and inhibits the development of melanoma in vivo by upregulating FADD. ADT-OH has the potential for the research of cancer diseases.	price>
R-R-2084	Edratide CAS No.433922-67-9	Edratide (TV 4710)/CAS No.433922-67-9 is a synthetic peptide of 19 amino acid based on the complementarity-determining region 1 (CDR1) of a human anti-DNA antibody that expresses a major idiotype denoted 16/6 Id. Edratide reduces the rates of apoptosis (Apoptosis) and down-regulates of caspase-8 and caspase-3, up-regulates Bcl-xL. Edratide has the potential for the research of systemic lupus erythematosus (SLE).	price>
R-R-2085	MitoBloCK-6 CAS No.303215-67-0	MitoBloCK-6/CAS No.303215-67-0 is a potent Erv1/ALR inhibitor, with an IC50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 (IC50=1.4 μM). MitoBloCK-6 can induce apoptosis via cytochrome c release in hESCs.	price>
R-R-2086	ASK1-IN-2 CAS No.2541792-70-3	ASK1-IN-2/CAS No.2541792-70-3 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can be used for the research of ulcerative colitis.	price>

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