API-1 CAS No.36707-00-3
API-1 CAS No.36707-00-3
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-2111 | 1mg | 300.00 | + Add to cart |
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| R-R-2111 | 2mg | 500.00 | + Add to cart |
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Product description
API-1/CAS No.36707-00-3, a potent Akt/PKB inhibitor, binds to the PH domain and inhibits Akt membrane translocation. API-1 efficiently reduces the phosphorylation levels of Akt with an IC50 of ∼0.8 μM. API-1 is selective for PKB and does not inhibit the activation of PKC, and PKA. API-1 also induces apoptosis by synergizing with TNF-related apoptosis-inducing ligand (TRAIL).
| Appearance | N/A |
|---|---|
| Molecular Weight | 337.29 |
| Purity | >90% |
| CAS | 36707-00-3 |
| Formula | C13H15N5O6 |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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