Product apis-apoptosis

Home > products > apis> apoptosis

Catalog	name	Description	price
R-R-2007	Phellamurin CAS No.52589-11-4	Phellamurin/CAS No.52589-11-4 is a plant flavonone glycoside from the leaves of Phellodendron amurense and inhibits intestinal P-glycoprotein. Phellamurin also inhibits egg laying by Papilio protenor. Phellamurin induces cells apoptosis and has anti-tumor activity.	price>
R-R-2008	Polyinosinic-polycytidylic acid sodium CAS No.42424-50-0	Polyinosinic-polycytidylic acid (Poly(I:C)) sodium/CAS No.42424-50-0 is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid sodium can directly trigger cancer cells to undergo apoptosis.	price>
R-R-2009	PFI-90 CAS No.53995-62-3	PFI-90/CAS No.53995-62-3 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action. PFI-90 induces apoptosis and myogenic differentiation, resulting in the cell death increased. PFI-90 has the potential for the antitumor activity. (patent WO2021101929A1).	price>
R-R-2010	Soyasaponin III CAS No.55304-02-4	Soyasaponin III/CAS No.55304-02-4, a monodesmodic oleanane triterpenoid, is one of the main potentially bioactive saponins found in soy (Glycine max) and related products. Soyasaponin III can induce apoptosis in Hep-G2 cells.	price>
R-R-2011	PDMP hydrochloride CAS No.73257-80-4	PDMP hydrochloride/CAS No.73257-80-4 is a glucosylceramide synthase (GCS) inhibitor. PDMP hydrochloride induces apoptosis in K562/A02 cells. PDMP hydrochloride can be used in cancer (such as leukemia) research.	price>
R-R-2012	Raptinal CAS No.1176-09-6	Raptinal/CAS No.1176-09-6, a agent that directly activates caspase-3, initiates intrinsic pathway caspase-dependent apoptosis. Raptinal is able to rapidly induce cancer cell death by directly activating the effector caspase-3, bypassing the activation of initiator caspase-8 and caspase-9.	price>
R-R-2013	HC-Toxin CAS No.83209-65-8	HC-Toxin/CAS No.83209-65-8, a cyclic tetrapeptide, is a potent HDAC inhibitor with an IC50 of 30 nM. HC-Toxin induces tumor cell apoptosis and has anticancer effects.	price>
R-R-2014	SIRT7 inhibitor 97491 CAS No.1807758-81-1	SIRT7 inhibitor 97491/CAS No.1807758-81-1, a potent SIRT7 inhibitor with an IC50 of 325 nM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway.	price>
R-R-2015	Azoxystrobin CAS No.131860-33-8	Azoxystrobin/CAS No.131860-33-8 is a broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis.	price>
R-R-2016	STAT3-IN-3 CAS No.2361304-26-7	STAT3-IN-3/CAS No.2361304-26-7 is a potent and selective inhibitor of signal transducer and activator of transcription 3 (STAT3), with anti-proliferative activity. STAT3-IN-3 induces apoptosis in breast cancer cells. STAT3-IN-3 acts as a promising mitochondria-targeting STAT3 inhibitor for cancer research.	price>

...