Product apis-apoptosis

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Catalog	name	Description	price
R-R-1997	Flunisolide CAS No.3385-03-3	Flunisolide/CAS No.3385-03-3 is a corticosteroid, which is an orally active glucocorticoid receptor activator with anti-inflammatory activity. Flunisolide can induce eosinophil apoptosis, and is used for the research of asthma or rhinitis, and inflammation.	price>
R-R-1998	Crolibulin CAS No.1000852-17-4	Crolibulin (EPC2407)/CAS No.1000852-17-4 is a tubulin polymerization inhibitor, with potent apoptosis induction and cell growth inhibition. Crolibulin has anti-tumor activity. Crolibulin also has cardiovascular toxicity and neurotoxicity.	price>
R-R-1999	Fludarabine triphosphate trisodium	Fludarabine triphosphate (F-ara-ATP) trisodium, the active metabolite of Fludarabine (HY-B0069), is a potent, noncompetitive and specific inhibitor of DNA primase, with an IC50 of 2.3 μM and a Ki of 6.1 μM. Fludarabine triphosphate trisodium inhibits DNA synthesis by blocking DNA primase and primer RNA formation. Fludarabine triphosphate trisodium inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis.	price>
R-R-2000	Golimumab CAS No.476181-74-5	Golimumab (CNTO-148)/CAS No.476181-74-5 is a potent human IgG1 TNFα antagonist monoclonal antibody. Golimumab has anti-inflammation activitity and inhibits IL-6 and IL-1β production. Golimumab acts via targeting and neutralizing TNF to prevent inflammation and destruction of cartilage and bone. Golimumab has the anticancer activity and induces cell apoptosis.	price>
R-R-2001	2-Hydroxy-3-methylanthraquinone CAS No.17241-40-6	2-Hydroxy-3-methylanthraquinone (compound 1)/CAS No.17241-40-6 is a natural compound isolated from a water extract of Hedyotis diffusa WILLD. 2-Hydroxy-3-methylanthraquinone shows inhibitory activity against protein tyrosine kinases v-src and pp60src, and induces growth arrest and apoptosis in the HepG2 cancer cells.	price>
R-R-2002	TH1834 CAS No.2108830-08-4	TH1834/CAS No.2108830-08-4 is a specific Tip60 (KAT5) histone acetyltransferase (HAT) inhibitor. TH1834 induces apoptosis and increases DNA damage in breast cancer. TH1834 does not affect the activity of related histone acetyltransferase MOF. Anticancer activity.	price>
R-R-2003	Pogostone CAS No.23800-56-8	Pogostone/CAS No.23800-56-8 is isolated from patchouli oil with anti-bacterial and anti-cancer activities. Pogostone inhibits both gram negative and gram positive bacteria, also show inhibitory effect on corynebacterium xerosis with a MIC value of 0.098 µg/ml . Pogostone induces cell apoptosis and autophagy.	price>
R-R-2004	TH1834 dihydrochloride CAS No.2108830-09-5	TH1834 dihydrochloride/CAS No.2108830-09-5 is a specific Tip60 (KAT5) histone acetyltransferase inhibitor. TH1834 dihydrochloride induces apoptosis and increases DNA damage in breast cancer. TH1834 dihydrochloride does not affect the activity of related histone acetyltransferase MOF. Anticancer activity.	price>
R-R-2005	NAE-IN-M22 CAS No.864420-54-2	NAE-IN-M22/CAS No.864420-54-2 is a potent, selective and reversible inhibitor of NEDD8 activating enzyme (NAE), with potency in micromolar range. NAE-IN-M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells. NAE-IN-M22 also can inhibit tumor growth in vivo.	price>
R-R-2006	UBX1325 CAS No.2271269-01-1	UBX1325/CAS No.2271269-01-1 is an Bcl-xL inhibitor that promotes apoptosis in senescent cells. UBX1325 is a potent anti-aging agent that can be used in studies of age-related eye diseases such as diabetic macular oedema (DME), age-related macular degeneration (AMD) and diabetic retinopathy (DR).	price>

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