Product apis-apoptosis

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Catalog	name	Description	price
R-R-2017	STAT3-IN-11 CAS No.2503096-50-0	STAT3-IN-11 (7a)/CAS No.2503096-50-0 is a selective STAT3 inhibitor that inhibits the phosphorylation of STAT3 at site pTyr705. STAT3-IN-11 inhibits the phosphorylation of downstream genes (Survivin and Mcl-1) without affecting its upstream tyrosine kinases (Src and JAK2) levels and p-STAT1 expression. STAT3-IN-11 can induce cancer cell apoptosis, which is potential for the discovery of effective STAT3 inhibitors and antitumor agents against cancers.	price>
R-R-2018	13-Methyltetradecanoic acid CAS No.2485-71-4	13-Methyltetradecanoic acid (13-MTD)/CAS No.2485-71-4, a saturated branched-chain fatty acid with potent anticancer effects. 13-Methyltetradecanoic acid induces apoptosis in many types of human cancer cells.	price>
R-R-2019	Alexidine dihydrochloride CAS No.1715-30-6	Alexidine dihydrochloride/CAS No.1715-30-6 is an anticancer agent that targets a mitochondrial tyrosine phosphatase, PTPMT1, in mammalian cells and causes mitochondrial apoptosis. Alexidine dihydrochloride has antifungal and antibiofilm activity against a diverse range of fungal pathogens.	price>
R-R-2020	MY-943	MY-943 is a potent tubulin polymerization and LSD1 inhibitor with anticancer activity. MY-943 induces G2/M phase arrest and apoptosis, and inhibits cell migration. MY-943 can be used for gastric cancer research.	price>
R-R-2021	Lupiwighteone CAS No.104691-86-3	Lupiwighteone/CAS No.104691-86-3 is an isoflavone present widely in wild-growing plants, with antioxidant, antimicrobial and anticancer effects. Lupiwighteone induces caspase-dependent and -independent apoptosis on human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway.	price>
R-R-2022	Carubicin hydrochloride CAS No.52794-97-5	Carubicin hydrochloride/CAS No.52794-97-5 is a microbially-derived compound. Carubicin hydrochloride is an effective inhibitor of VHL-defective (VHL−/−) CCRCC cell proliferation. Carubicin hydrochloride also induces apoptosis by a mechanism independent of p53 or hypoxia-inducible factor HIF2. Carubicin hydrochloride has the potential for the research of cancer diseases.	price>
R-R-2023	NU9056 CAS No.1450644-28-6	NU9056/CAS No.1450644-28-6 is a potent and selective Tip60 (KAT5) histone acetyltransferase inhibitor with an of 2 µM. NU9056 shows >16-fold selectivity for Tip60 over PCAF, p300 and GCN5. NU9056 induces apoptosis of prostate cancer cells.	price>
R-R-2024	MI-192 CAS No.1415340-63-4	MI-192/CAS No.1415340-63-4 is a selective HDAC2 and HDAC3 inhibitor with IC50s of 30 nM and 16 nM, respectively. MI-192 is more selective for HDAC2/3 than other HDAC isomers.MI-192 induces myeloid leukaemic cells apoptosis. Anticaner and neuroprotective activities.	price>
R-R-2025	7,8-Dihydroneopterin CAS No.1218-98-0	7,8-Dihydroneopterin/CAS No.1218-98-0, an inflammation marker, induces cellular apoptosis in astrocytes and neurons via enhancement of nitric oxide synthase (iNOS) expression. 7,8-Dihydroneopterin can be used in the research of neurodegenerative diseases.	price>
R-R-2026	K-7174 dihydrochloride CAS No.191089-60-8	K-7174 dihydrochloride/CAS No.191089-60-8 is an orally active proteasome and GATA inhibitor. K-7174 dihydrochloride is a cell adhesion inhibitor. K-7174 dihydrochloride induces cell apoptosis. K-7174 dihydrochloride shows antitumor activities, it can be used for the research of cancer.	price>

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