Product apis-apoptosis

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Catalog	name	Description	price
R-R-1610	Estramustine phosphate sodium CAS No.52205-73-9	Estramustine phosphate sodium/CAS No.52205-73-9, an estradiol analog, is an orally active antimicrotubule chemotherapy agent. Estramustine phosphate sodium depolymerises microtubules by binding to microtubule associated proteins (MAPs) and/or to tubulin. Estramustine phosphate sodium can interfere mitosis, trigger cell death and induce apoptosis, which can be used for the research of cancer like prostate cancer.	price>
R-R-1611	Eldecalcitol CAS No.104121-92-8	Eldecalcitol (ED-71)/CAS No.104121-92-8 is an orally active vitamin D3 analogue, inhibits bone resorption and increases bone mineral density. Eldecalcitol (ED-71) displays anti-tumor effect and inhibits cell proliferation, migration and induces apoptosis by suppressing GPx-1.	price>
R-R-1612	(E)-Methyl 4-coumarate CAS No.19367-38-5	(E)-Methyl 4-coumarate (Methyl 4-hydroxycinnamate)/CAS No.19367-38-5, found in several plants, such as Allium cepa or Morinda citrifolia L. leaves. (E)-Methyl 4-coumarate cooperates with Carnosic Acid in inducing apoptosis and killing acute myeloid leukemia cells, but not normal peripheral blood mononuclear cells. Antioxidant and antimicrobial activity.	price>
R-R-1613	Kauran-16,17-diol CAS No.16836-31-0	Kauran-16,17-diol (ent-Kauran-16β,17-diol)/CAS No.16836-31-0, a natural diterpene, posseses anti-tumor and inducing-apoptosis activity, with a IC50 of 17 μM on inhibiting NO production in LPS-stimulated RAW 264.7 macrophages.	price>
R-R-1614	Ionomycin CAS No.56092-81-0	Ionomycin (SQ23377)/CAS No.56092-81-0 is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin also induces the activation of protein kinase C (PKC).	price>
R-R-1615	Tyrphostin AG 879 CAS No.148741-30-4	Tyrphostin AG 879 (AG 879)/CAS No.148741-30-4 is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation (IC50 of 10 μM), but not TrKB and TrKC. Tyrphostin AG 879 is also a selective ErbB2 tyrosine kinase inhibitor with an IC50 of 1 μM, and has at least 500-fold higher selectivity to ErbB2 than EGFR. Tyrphostin AG 879 has anticancer activity.	price>
R-R-1616	Fluorizoline CAS No.1362243-70-6	Fluorizoline/CAS No.1362243-70-6 selectively and directly binds to prohibitin 1 (PHB1) and 2 (PHB2), and induces apoptosis. Fluorizoline reduces chronic lymphocytic leukemia (CLL) cell viability through the upregulation of NOXA and BIM. Fluorizoline exerts antitumor action in a p53-independent manner.	price>
R-R-1617	AK-778-XXMU CAS No.1227045-76-2	AK-778-XXMU/CAS No.1227045-76-2 is a potent inhibitor of DNA Binding 2 (ID2) antagonist with a KD of 129 nM. AK-778-XXMU can inhibit cell migration and invasion of glioma cell lines, induce apoptosis, and more importantly, slow down the tumor growth.	price>
R-R-1618	MPP dihydrochloride CAS No.911295-24-4	MPP dihydrochloride/CAS No.911295-24-4 is a potent and selective ER (estrogen receptor) modulator. MPP dihydrochloride induces significant apoptosis in the endometrial cancer and oLE cell lines. MPP dihydrochloride reverses the positive effects of beta-estradiol. MPP dihydrochloride has mixed agonist/antagonist action on murine uterine ERalpha in vivo.	price>
R-R-1619	Niraparib tosylate hydrate CAS No.1613220-15-7	Niraparib (MK-4827) tosylate hydrate/CAS No.1613220-15-7 is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib tosylate hydrate leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.	price>

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