Product apis-Inhibitor-customization

Home > products > apis> Inhibitor-customization

Catalog	name	Description	price
R-C-1330	MCC950 sodium（CP-456773 sodium; CRID3 sodium salt） CAS No. : 256373-96-3	MCC950 sodium(CP-456773 sodiumCRID3 sodium salt)is a potent, selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively.	price>
R-C-1348	WAY181187.HCl CAS：554403-08-6	WAY-181187 is a potent and selective 5-HT6 receptor agonist.WAY-181187 possesses high affinity binding(2.2 and 4.8 nM,respectively)at the human 5-HT6 receptor and profile as full receptor agonists (WAY-181187:EC50=6.6 nM,Emax=93%).	price>
R-C-1349	fluoroclebopride CAS No. 154540-49-5	Fluoroclebopride is a benzamide analog that is used in positron emission tomography(PET)applications.It binds reversibly to dopamine receptors(Kis= 0.95,5.7,5.46,and 144 nM for D2-like,D2(long),D3,and D4 receptors,respectively, in radioligand binding assays).It is selective for these receptors over D1, serotonin 5-HT2,and α2-adrenergic receptors(Kis=>10,000,283,and 1,300 nM, respectively).	price>
R-C-1363	Finafloxacin Hydrochloride CAS：209342-41-6	Finafloxacin hydrochloride is used to prepare naphthyridonecarboxylic acid derivatives as drugs for treatment therapy of H.pylori infections and associated gastroduodenal illnesses.	price>
R-C-1365	Nosiheptide CAS:56377-79-8	Nosiheptide(Multhiomycin),a thiopeptide antibiotic produced by Streptomyces actuosus,inhibits bacterial protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core.Nosiheptide has been widely used as a feed additive for animal growth.	price>
R-C-1372	ACT-678689 CAS：1783256-96-1	ACT-678689 is a potent inhibitor of tryptophan hydroxylase 1(TPH1).	price>
R-C-1394	RO4938581 CAS：883093-10-5	RO 4938581 is a potent and selective GABAA α5 inverse agonist,with a Ki of 4.6 nM for GABAA α5β3γ2a,and shows a lower affinity at α1β3γ2a,α2β3γ2a, α3β3γ2a (Ki,174,185,80 nM,respectively).	price>
R-C-1400	MK-7655 CAS:1174018-99-5	Relebactam, also known as MK-7655,a potent and selective β-lactamase inhibitor. At a concentration of 4 mg/L,MK-7655 reduced imipenem MICs for Enterobacteriaceae with KPC carbapenemases from 16-64 mg/L to 0.12-1 mg/L.MK-7655 potentiated imipenem against Enterobacteriaceae with KPC carbapenemases or combinations of β-lactamase and impermeability,but not those with metallo-carbapenemases.It augmented the activity of imipenem against P.aeruginosa in general and OprD mutants in particular.	price>
R-C-1422	Tipiracil HCL CAS:183204-72-0	Tipiralacil,also known as TPI,is a thymidine phosphorylase inhibitor(TPI).	price>
R-C-1424	Carbazeran CAS:70724-25-3	Carbazeran is an Aldehyde oxidase(AO)substrate and potent phosphodiesterase PDE-II and PDE-III inhibitor that produces concentration-dependent positive inotropic responses.Carbazeran shows chronotropic and inotropic effect in vivo (EC50=100μM,ionotropic effects,independent of adrenergic mechanisms).It potently inhibits cAMP hydrolysis.In humans,the compound is almost completely cleared via 4-hydroxylation to the phthalazinone metabolite by AO.	price>

...