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Catalog	name	Description	price
R-C-1528	CHIR-090 CAS: 728865-23-4	CHIR-090 is a potent,slow,tight-binding inhibitor of the LpxC deacetylase.It binds to E.coli LpxC with a Ki of 4.0nM.	price>
R-C-1582	Motolimod (VTX-2337) CAS:926927-61-9	Motolimod(VTX-2337)is a selective and potent Toll-like receptor 8(TLR8)agonist with EC50 of 100 nM,>50-fold selectivity over TLR7.	price>
R-C-1584	GRT6005(Cebranopadol) CAS:863513-91-1	Cebranopadol(GRT-6005)is a Opioid Receptor Agonist with agonistic activity at nociceptin/orphanin FQ and opioid receptors.Cebranopadol displays analgesic, antiallodynic and antihyperalgesic properties in several rat models of acute nociceptive,inflammatory,cancer and neuropathic pain.In contrast to classical opioids,it has a higher analgesic potency in models of neuropathic pain than in acute nociceptive pain.Even at higher analgesic doses,cebranopadol does not induce motor coordination deficits or respiratory depression in rats.	price>
R-C-1610	Abivertinib maleate CAS:1557268-88-8	Abivertinib,also known as avitinib,AC0010 or AC0010MA,is an orally available, irreversible,epidermal growth factor receptor(EGFR)mutant-selective inhibitor, with potential antineoplastic activity.Upon oral administration,avitinib covalently binds to and inhibits the activity of mutant forms of EGFR,including the drug-resistant T790M EGFR mutant,which prevents signaling mediated by mutant forms of EGFR.This may both induce cell death and inhibit tumor growth in EGFR-mutated tumor cells.EGFR,a receptor tyrosine kinase that is mutated in a variety of cancers,plays a key role in tumor cell proliferation and tumor vascularization.As this agent is selective towards mutant forms of EGFR,its toxicity profile may be reduced when compared to non-selective EGFR inhibitors, which also inhibit wild-type EGFR.	price>
R-C-1611	SAR348830 CAS:1462949-64-9	SAR348830 is novel potent and selective inhibitor of anaplastic lymphoma kinase (ALK).	price>
R-C-1624	HUHS015 CAS:1453097-13-6	HUHS015 is a potent PCA-1/ALKBH3 inhibitor both in vitro and in vivo.The bioavailability(BA)of HUHS015 was 7.2% in rats after oral administration. Continuously administering HUHS015 significantly suppressed the growth of DU145 cells,which are human hormone-independent prostate cancer cells,in a mouse xenograft model without untoward effects.	price>
R-C-1629	CUDC-908 CAS:1235449-52-1	BEBT-908(CUDC-908,PI3Kαinhibitor 1,MDK9521,PI3Kα-IN-243)is a potent selective inhibitor of PI3Kα with IC50<0.1μM.BEBT-908 also inhibits HDAC with IC50≤1μM.	price>
R-C-1630	Danirixin (GSK1325756) CAS：954126-98-8	Danirixin(GSK1325756)is a small molecule,non-peptide, high affinity(IC50 for CXCL8(IL-8)binding = 12.5nM),selective,and reversible CXCR2 antagonist.	price>
R-C-1633	GSK2814338 CAS：1420367-28-7	GSK2814338,also known as Lp-PLA2 -IN-1,is a Lp-PLA2 inhibitor.	price>
R-C-1635	GSK3039294 CAS:1819986-22-5	GSK3039294 is an orally available small molecule inhibitor of serum amyloid P component(SAP)binding to amyloid fibrils for the depletion of serum amyloid-P(SAP)component from the circulation.	price>

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