Product block-copolymer-plga-peg

Home > products > block-copolymer> plga-peg

Catalog	name	Description	price
R-C-7186	PLGA-PEG-EDTA	EDTA-PEG-PLGA,it couples PLGA,PEG,and EDTA through chemical bonds to form a three-stage copolymer.EDTA,as a chelating agent,can bind to metal ions such as gadolinium and iron,enhancing the targeting and functionalization ability of materials.This product is mainly used in the fields of drug delivery,targeted therapy,and biomaterials.	price>
R-C-5611	PLGA10K-PEG2K-MAL	PLGA-PEG-MAL, Poly(L-lactide-co-glycolide)-Polyethyleneglycol-Maleimide is a biodegradable functional amphiphilic block copolymer.The PEGhydrophilic is capped a maleimide group, and the PLGA hydrophobic blockterminates with a hydroxyl group.PLGA10k-PEG2k-MAL can self assemble into PLGA core/PEG shellpolymeric micelles.Maleimide on the micelle surface can conjugate withpeptides, antibodies, proteins and others which contain Thiol groups on thesurface.We can provide peg molecular weights of 1k, 2k, 3.4k, 5k, and 10k for this product.	price>
R-C-7192	PLGA20k-PEG2k-GPLGVRGK-MAL 50:50	PLGA-PEG-GPLGVRGK-MAL,PLGA-PEG-GPLGVRGK-MAL is a multifunctional polymer composed of poly(lactic acid glycolic acid)copolymer(PLGA),polyethylene glycol(PEG),targeted peptide GPLGVRGK,and maleimide (MAL).PLGA provides biodegradability and controlled release function,and the degradation products are lactic acid and glycolic acid.PEG enhances water solubility and blood circulation time,reduces non-specific adsorption,and GPLGVRGK peptide targets integrin α v β 3 on the surface of tumor cells,achieving tumor specific delivery.The MAL group couples with peptides through thiol maleimide reaction to form stable covalent bonds.	price>
R-C-5614	PLGA10K-TK-PEG5K-carboxylic-acid	PLGA-TK-PEG-COOH,By combining PLGA,TK,and PEG-COOH,the resulting polymer can possess properties of controlled drug release,TK inhibition, and enhanced stability.The PLGA component allows for sustained release of TK inhibitors,providing a prolonged therapeutic effect.The PEG-COOH segment may offer improved biocompatibility,solubility, and potential sites for conjugation or further modification.	price>
R-C-7196	PLGA20000-F127-SH 50:50	PLGA20000-F127-SH is an amphiphilic block copolymer composed of polylactic acid hydroxyacetic acid copolymer(PLGA)and Pluronic F127,with thiol groups(-SH)at the ends. This material is commonly used in fields such as drug delivery and biocompatible materials.	price>
R-C-7213	PLGA-SS-PEG-CY7	PLGA-SS-PEG-CY7,PLGA provides biodegradability and the degradation product is lactic acid, suitable for in vivo drug release.The disulfide bond(SS)reduction sensitive structure can be broken in highly reducing environments within tumors or cells, achieving controlled drug release.PEG enhances water solubility, prolongs in vivo circulation time, and reduces immune recognition.CY7 is a near-infrared fluorescent dye(excitation wavelength of approximately 750 nm,emission wavelength of 770-780 nm),suitable for deep tissue imaging and real-time tracking.	price>
R-C-5640	PALA20k-b-PEG2000-COOH	Poly(alpha-lipoic acid) (P-ALA) refers to a polymer derived from alpha-lipoic acid (ALA), also known as thioctic acid. Alpha-lipoic acid is a naturally occurring antioxidant that plays a crucial role in cellular metabolism.The presence of PEG in the copolymer offers advantages such as increased stability, prolonged circulation time, and reduced immunogenicity.The carboxylic acid functional group (COOH) on the end of the PEG chain can be utilized for further functionalization or conjugation of molecules, drugs, or targeting ligands through covalent bonding.	price>
R-C-5660	PLGA2000-SS-PEG2000-Glu-OtBu, 50:50	PLGA-SS-PEG-Glu-OtBu,poly(lactic-co-glycolic acid)PLGA is typically synthesized by copolymerizing lactic acid and glycolic acid,resulting in a polymer with varying ratios of the two monomers.The presence of a disulfide bond in the polymer allows for redox-responsive release of the encapsulated drugs,making it an attractive feature for targeted drug delivery systems.Glu-OtBu refers to glutamic acid-O-t-butyloxycarbonyl,a protected form of glutamic acid.Glutamic acid is an amino acid commonly found in proteins and peptides.The incorporation of glutamic acid into the polymer structure can potentially provide a substrate for enzymatic degradation,allowing for controlled release of the drug.	price>
R-C-5670	PLGA10k-SS-PEG2k-SS-PLGA10k 50/50	PLGA is a biodegradable and biocompatible polymer commonly used in drug delivery systems and tissue engineering.The inclusion of thiolated polyethylene glycol (PEG)in the copolymer structure provides several advantages.PEG is a hydrophilic polymer that improves the water solubility and stability of the copolymer.Disulfide linkages are susceptible to reduction in a reducing environment,and their cleavage can be triggered to release drugs or cargo encapsulated within the copolymer.	price>
R-C-5677	PLGA20K-PEG2K-transferrin	Transferrin is a protein present in the body that binds to transferrin receptors, which are overexpressed on the surface of certain cells, including cancer cells. By conjugating transferrin to PLGA-PEG, the bioconjugate can specifically target cells that have high levels of transferrin receptors.The PLGA-PEG-transferrin combining these components, the bioconjugate can improve the specificity and efficacy of drug delivery, particularly for diseases where transferrin receptor expression is upregulated.	price>

...