Product block-copolymer-plga-peg

Home > products > block-copolymer> plga-peg

Catalog	name	Description	price
R-C-5660	PLGA2000-SS-PEG2000-Glu-OtBu, 50:50	PLGA-SS-PEG-Glu-OtBu,poly(lactic-co-glycolic acid)PLGA is typically synthesized by copolymerizing lactic acid and glycolic acid,resulting in a polymer with varying ratios of the two monomers.The presence of a disulfide bond in the polymer allows for redox-responsive release of the encapsulated drugs,making it an attractive feature for targeted drug delivery systems.Glu-OtBu refers to glutamic acid-O-t-butyloxycarbonyl,a protected form of glutamic acid.Glutamic acid is an amino acid commonly found in proteins and peptides.The incorporation of glutamic acid into the polymer structure can potentially provide a substrate for enzymatic degradation,allowing for controlled release of the drug.	price>
R-C-5670	PLGA10k-SS-PEG2k-SS-PLGA10k 50/50	PLGA is a biodegradable and biocompatible polymer commonly used in drug delivery systems and tissue engineering.The inclusion of thiolated polyethylene glycol (PEG)in the copolymer structure provides several advantages.PEG is a hydrophilic polymer that improves the water solubility and stability of the copolymer.Disulfide linkages are susceptible to reduction in a reducing environment,and their cleavage can be triggered to release drugs or cargo encapsulated within the copolymer.	price>
R-C-5677	PLGA20K-PEG2K-transferrin	Transferrin is a protein present in the body that binds to transferrin receptors, which are overexpressed on the surface of certain cells, including cancer cells. By conjugating transferrin to PLGA-PEG, the bioconjugate can specifically target cells that have high levels of transferrin receptors.The PLGA-PEG-transferrin combining these components, the bioconjugate can improve the specificity and efficacy of drug delivery, particularly for diseases where transferrin receptor expression is upregulated.	price>
R-C-5684	PLGA(1.8W-2W）50:50-maleimide	Poly (L-lactide co glycolide)-Maleimide,PLGA-MAL,PLGA is a biodegradable and biocompatible polymer composed of lactic acid and glycolic acid. It has been widely used in drug delivery systems and tissue engineering due to its controlled release properties and ability to degrade in the body over time.	price>
R-C-5685	mPEG2K-SE-SE-PLGA10K(75/25)	PLGA-SE-SE-mPEG,mPEG is a hydrophilic polymer that improves the water solubility and biocompatibility of the copolymer.PLGA and PEG are connected through disulfide bonds, and when encountering reducing substances, the disulfide bonds can break, which can accelerate the release of drugs.	price>
R-C-5686	mPEG2K-hyd-PLGA5K	Poly(L-lactide-co-glycolide)-Hydrazone-Polyethylene glycol,Hydrazone bond has pH response effect. PLGA was linked to hydrazone bond and PEG Alkyne was coupled to form micelles with pH response. PH responsive polymer micelles can exist stably in normal tissue, but in the area of slightly acidic tumor tissue, the nucleus or shell of micelles undergo protonation or chemical reaction, which leads to the change of physical properties, the destruction of micelle structure,the rapid release of drugs from micelles to tumor tissue, and the better effect of killing cancer cells.	price>
R-C-5752	PLGA10000-PEG3400-HHLGGAKQAGDV-NH2	PLGA-PEG-HHLGGAKQAGDV-NH2,PLGA-PEG-HHLGGAKQAGDV-amine,PLGA is a biodegradable and biocompatible polymer commonly used in drug delivery systems.PEG is a hydrophilic polymer,It enhances the biocompatibility and tolerability of drug delivery systems.By conjugating PLGA with PEG and the HHLGGAKQAGDV peptide sequence, the resulting PLGA-PEG-HHLGGAKQAGDV-amine conjugate provides a platform for targeted drug delivery.The PLGA core enables encapsulation and controlled release of therapeutic agents, while PEG imparts stealth properties to avoid rapid clearance by the immune system.The HHLGGAKQAGDV peptide sequence allows for specific targeting and enhanced cellular uptake.	price>
R-C-5762	HA-PLGA@CY5.5	Hyaluronic acid (HA) is a natural polymer found in the extracellular matrix, which provides structural support to cells and tissues.Poly(lactic-co-glycolic acid) (PLGA) is a synthetic polymer that is commonly used in drug delivery systems. It is biodegradable and has low toxicity, making it suitable for biomedical applications.Cyanine 5.5 (CY5.5) dye is a fluorescent dye that emits near-infrared light, making it ideal for imaging applications.	price>
R-C-5763	PLGA@CY5.5	Poly(lactic-co-glycolic acid) (PLGA) is a biodegradable and biocompatible polymer commonly used in drug delivery systems.Cyanine 5.5 (CY5.5) is a near-infrared fluorescent dye that emits light in the red spectrum. It is often used as a contrast agent or imaging probe due to its favorable properties, including high fluorescence intensity, high photostability,and low toxicity.These nanoparticles or conjugates can be used for various biomedical applications,such as targeted drug delivery,imaging, or tracking.	price>
R-C-5764	HA-PLGA@Shikonin	Shikonin is a natural compound derived from plants, particularly from the roots of Lithospermum erythrorhizon. It has shown numerous potential therapeutic applications, including anti-inflammatory, anti-cancer, and immunomodulatory effects. Incorporating shikonin into HA-PLGA nanoparticles allows for controlled and targeted delivery of shikonin to specific tissues or cells.	price>

...