Catalog |
name |
Description |
price |
R-C-5414 |
PLGA-PAMAM G5 (100-200nm) |
PAMAM G5 represents a specific generation (generation 5) of poly(amidoamine) dendrimers. PAMAM dendrimers are highly branched, three-dimensional structures with amino groups on their surface. The dendrimers generation refers to the number of layers branching outward from the core, with higher generations having more branches. |
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R-C-5419 |
PLGA-TK-PEG2000-SS-31 20000(50:50) |
PLGA can encapsulate drugs within its matrix and facilitate their controlled release, making it suitable for sustained drug delivery.The TK sequence helps in specific delivery and accumulation of drugs or therapeutic agents at the desired location.PEGylation improves the stability, solubility, and bioavailability of the compound, as well as reducing non-specific interactions and immunogenicity.SS-31 is a mitochondria-targeting peptide. It specifically targets the mitochondria, the powerhouse of the cell, and has shown potential in protecting against oxidative stress and mitochondrial dysfunction. |
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R-C-5421 |
PLGA8K-PEG2K-CRTLTVRK(5-FITC)C |
The PLGA component provides sustained release and biodegradability, PEGylation improves stability and bioavailability, the CRTLTVRK sequence enables specific targeting, and the FITC label allows for fluorescence imaging capabilities. This compound can be utilized for targeted drug delivery, imaging, and potentially personalized therapy, depending on the specific target and therapeutic payload. |
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R-C-5422 |
PLGA8K-PEG2K-CRTLTVRKC |
PLGA is a biocompatible and biodegradable polymer commonly used for drug delivery systems. PEGylation helps improve the stability, solubility, and bioavailability of the compound while reducing non-specific interactions and immunogenicity.CRTLTVRK is a specific peptide sequence, often called a targeting peptide or ligand sequence. This sequence is designed to selectively bind to a specific receptor or target site in the body. The sequence CRTLTVRK may have been chosen for its specific binding properties to a particular target of interest. |
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R-C-5430 |
PLGA3K-PEG2K-KAWAECRPPDDGLC |
PLGA3K provides biodegradability and controlled release capabilities.PEG2K enhances solubility, biocompatibility, and circulation time.KAWAECRPPDDGLC may contribute to targeting specific receptors or improving cellular interactions. |
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R-C-5435 |
PLGA-TK-PEG-RGD |
PLGA is a biodegradable and biocompatible polymer commonly used in drug delivery systems. It can encapsulate drugs and release them in a controlled manner.RGD is a peptide sequence composed of arginine (R), glycine (G), and aspartic acid (D) residues.This combination allows for the integration of various properties and functionalities, making it potentially applicable in targeted drug delivery or tissue engineering applications. |
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R-C-5443 |
β-CD-g-PLGA5k |
The β-Cyclodextrin component allows the copolymer to form inclusion complexes with hydrophobic drugs or molecules, enhancing their solubility and stability. This property is particularly useful for drug delivery purposes, as it can increase the bioavailability and therapeutic efficacy of poorly soluble drugs.PLGA provides the copolymer with biodegradability, biocompatibility, and controlled release characteristics. |
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R-C-5448 |
PLGA11K-PEG5K-Angiopep-2 |
PLGA is a biodegradable and biocompatible polymer commonly used in nanoparticle formulations. It allows for the controlled release of encapsulated drugs over time and provides stability to the nanoparticles.PEG is a hydrophilic polymer used as a coating material to enhance the stability, circulation time,and biocompatibility of nanoparticles. Angiopep-2 is a peptide sequence derived from the Kunitz domain of tissue factor pathway inhibitor-2 (TFPI-2). |
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R-C-5449 |
PLGA10K-PEG5K-PEI2.5K-CY5.5(50/50) |
CY5.5 is a near-infrared fluorescent dye that enables the visualization and tracking of nanoparticles in tissues and cells. It emits fluorescence in the near-infrared spectrum, which has improved tissue penetration and reduced background autofluorescence, making it suitable for in vivo imaging applications.The PLGA core provides stability and controlled release of the cargo, while PEGylation enhances stability, bioavailability, and circulation time. PEI promotes efficient cellular uptake and intracellular delivery of nucleic acids. |
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R-C-5457 |
PLGA-SS-PEG-AANL-KLVFFK(GGDGR)YIGSR MW:7600,2000 PLGA:75/25 |
PLGA-SS-PEG-AANL-KLVFFK(GGDGR)YIGSR creates a drug delivery system that possesses controlled-release capabilities, targeting functionalities, and cell adhesive properties. The PLGA core enables encapsulation of drugs while the SS bond allows for controlled drug release under reducing conditions. The PEG layer improves stability, solubility, and circulation time. The AANL peptide sequence serves as a targeting ligand, enabling specific delivery to cells overexpressing the corresponding receptor. |
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