Product phospholipids -phospholipid-peg-customization

Home > products > phospholipids > phospholipid-peg-customization

Catalog	name	Description	price
R-DS-0048	DSPE-PEG-NGR(ASP-Gly-Arg)-CD13	Polyethylene glycol phospholipid liposomes can be used for drug delivery,gene transfection and vaccine delivery.Polyethylene glycol phosphowax can significantly improve the blood circulation time and stabilize the drug package. These materials can also be used for targeted drug delivery by modifying surface ligands such as antibodies and peptides.The targeting peptide can target CD13 receptor which is over expressed in tumor neovascularization epithelial cells.	price>
R-DS-0049	DSPE-PEG-FAL	Non lysosomal cationic liposomes modify common cationic liposomes by introducing special fal peptides.Firstly,the product dspe-pec-fal was obtained by modifying dspe-peg-nh2 with fl polypeptide.The results of NMR and IR showed that the Al peptide was successfully connected to dspe-pec.Cationic lipid 2-dioleoylhydropropyl-3-n,N,k-trimethylammonium (DOTAP) was selected as cationic lipid,Liposomes modified by fal were prepared by film dispersion method using neutral auxiliary lipid dioleoyl phosphatidylethanolamine (DOPE) and the mixture of DSPE-PEC-NH2 and DSPE-PEG-FAL.	price>
R-DS-0050	DSPE-PEG2000-D4	Peptide ligands containing six amino acids were screened for tumor cell epidermal growth factor (EGFR).Fluorescent liposomes containing D4 peptide were injected into tumor bearing mice via tail vein.In vivo imaging of small animals showed that fluorescent liposomes not only accumulated in tumor,but also had strong fluorescence signal in brain.Using loperamide as the"probe"and DSPE-PEG2000-D4 micelles as carriers,we found that D4 peptide has the ability to cross the blood-brain barrier through hot water bath tail contraction and formalin induced pain in mice.	price>
R-DS-0051	DSPE-PEG2000-RLT	Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.	price>
R-DS-0052	DSPE-PEG5000-LTV	On the basis of PL(ID)NP nanoparticles,pl(V/D) np-ltv,a dual-mode CT/fluorescence nanoparticles targeting spontaneous breast cancer,was developed.HER2 targeted nanoparticles pl(I/D) np-ltv were prepared by modifying pl(I/D) NP with targeted phospholipid dspe-peg5000-ltv.The particle size of DLS was 64.9 ± 1.3 nm and had good serum stability.	price>
R-DS-0053	RPAKPAR-PEG-DSPE	A variety of receptors are highly expressed in brain tumor cells and blood-brain barrier,such as transferrin receptor,low-density lipoprotein receptor and so on. Therefore,the specific ligands of these receptors can be used as two-level target molecules for blood-brain barrier and brain tumor cells.	price>
R-DS-0054	DSPE-PEG2000-NGF	NGF is a kind of polypeptide with various activities,which widely exists in various tissues of animals.It can nourish the injured peripheral nerve and promote regeneration and repair.When the peripheral nerve is injured,its corresponding cell body and axon can use exogenous NGF to transport retrogradely through the injured axon,making NGF reach the corresponding cell body.After the complex process of anabolism,NGF can be extended,It promotes axonal myelination.	price>
R-DS-0055	DSPE-PEG-PVTRPPR	PVTRPPR was modified on the surface of stealth liposomes,and pvtrppr polypeptide was used as the targeting head group.The drug loaded stealth liposome could target the drug to the tumor blood vessels through the tumor penetrating peptide pvtrppr,and penetrate the whole tumor tissue directly,so as to improve the therapeutic effect of the drug.	price>
R-DS-0056	DSPE-PEG-T7(HAIYPRH)	T7(HAIYPRH) is a short peptide screened by phage display technology,which can specifically bind to TfR with a binding constant as high as 10 nmol·L −1. Moreover,due to the different binding sites,endogenous TF will not inhibit, but will promote the binding of T7 modified nanoparticles to TfR.Therefore,T7 is more suitable as a target molecule,and there are many reports on the application of T7 peptide alone.	price>
R-DS-0057	DSPE-PEG-R9	Cell penetrating peptide (CPP) is a kind of short peptide with strong penetration effect on cell membrane,which can promote cell uptake.Liposome modified by CPP can improve the rate of liposome entry into the cell,which is a new direction of targeted drug delivery carrier research.	price>

...