Product phospholipids -phospholipid-peg-customization

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Catalog	name	Description	price
R-DS-0040	DSPE-PEG-pPB(CSRNLIDC)	As a receptor targeted anticancer carrier,stearyl phosphatidylethanolamine polyethylene glycol (peg-ppb) polypeptides have been increasingly used to improve the effect of chemotherapy drugs.It has also been proved by experiments that it can enhance the targeting specificity of drugs,enhance the targeted absorption of drugs,improve the anti-tumor effect,and also can improve the original insoluble properties of some small molecule drugs.Peptide carrier targeting technology is known as a new generation of targeted drug development technology.	price>
R-DS-0041	DSPE peg affinity peptide p1c	Liposomes can passively enter tumor tissue through enhanced retention and retention effect (EPR).Compared with radiotherapy and chemotherapy alone, liposomes have certain clinical treatment advantages.However,due to the rapid blood flow,liposomes can not stay in the tumor site for a long time after entering the body through intravenous injection.However,the targeted liposome prepared by connecting peptide on the surface of liposome can reach the target site immediately after intravenous injection and stay in the tumor site for a long time.The drug released from the liposome can improve the therapeutic effect of tumor.	price>
R-DS-0041	DSPE-PEG-preS1	The pres/s coding region of hepatitis B virus encodes two polypeptides (PreS1 and preS2),which are larger than the virus surface antigen (s) protein,but are not abundant.Different from preS2 and S proteins,PreS1 protein preferentially located on circulating virus particles,but could not be effectively secreted in cultured mammalian cells.	price>
R-DS-0042	DSPE-PEG-HBVpreS1(2-21Aa)	Using HBVPreS1/2-21myr as target medium,long-acting circulating liposome (LCL) as drug carrier and fluorescein sodium (FS) as fluorescence mode to evaluate drugs,a novel drug delivery system targeting NTCP receptor was prepared by ethanol injection.HBVPreS1/2-21myr-peg2000-dspe was used as the raw material of liposome synthesis,mixed with soybean phospholipid,cholesterol and other liposome formula components,heated and prepared liposomes.	price>
R-DS-0043	DSPE-PEG2000-MAL-RGD(Arg-Gly-Asp-DPhe-Cys)	A novel amphiphilic polymer block (dspe-peg2000-mal-RGD)was synthesized by linking RGD peptide with dspe-peg2000-mal.the BODIPY fluorescent dye was self-assembled with dspe-peg2000-mal-RGD to obtain a water-soluble bodipy-pc-RGD fluorescent probe complex,The optical properties of the fluorescent probe were measured by field emission transmission electron microscope and fluorescence microscope.It was found that the fluorescent probe had regular morphology, uniform size,about 143 nm in diameter,and had good near-infrared fluorescence characteristics.	price>
R-DS-0044	DSPE-PEG3400-c(RGDfk)(cyclo (Arg-Gly-Asp-d-Phe-Lys))	Peptides as receptor targeted anti-tumor carrier are more and more used to improve the effect of chemotherapy drugs.It has been proved by experiments that peptides can improve the anti-tumor effect by enhancing the targeting specificity of drugs,enhancing the targeted absorption of drugs,and improving the original insoluble properties of some small molecular drugs.	price>
R-DS-1000	DSPE-PEG2000-CRGDK(Cys-Arg-Gly-Asp-Lys)	Polyethylene glycol phospholipid is an excellent material to form liposomes, which can be used for gene transfection,vaccine delivery,drug delivery and targeted drug use.Phospholipids are hydrophobic and hydrophilic.It can be used to modify protein drugs,peptide compounds,organic small molecule drugs,biomaterials and so on.CRGDK is a straight chain.	price>
R-DS-0045	DSPE-PEG3400-RGERPPR	DSPE conjugated polyethylene glycol is a combination of phospholipid and polyethylene glycol,which has hydrophilicity and hydrophobicity.Polyethylene glycol phospholipid liposomes can be used for drug delivery,gene transfection and vaccine delivery.Pegylated phospholipids can significantly improve blood circulation time and stabilize drug encapsulation.These materials can also be used for targeted drug delivery by modifying ligands with target surfaces such as antibodies and peptides.	price>
R-DS-0046	DSPE-PEG-c(RGDyK)	The immunogenicity of C (rgdyk)-peg-dspe was derived from C (rgdyk)-peg-dspe, which eventually led to serious life-threatening toxicity.However,C(rgdyk) itself had no ability to induce immune response.The results of antibody typing showed that IgG3 was the main subtype of specific IgG antibody of C (rgdyk) modified liposomes,and the antibody production rate was fast,suggesting that C (rgdyk) modified liposomes belonged to T cell independent type-2 (TI-2) antigen. At the same time,it was found that cytotoxic chemotherapeutic drugs could mask the immunogenicity of C (rgdyk) modified liposomes,but there might be safety problems when they were used to deliver molecular targeted drugs with good tumor cell specificity and low adverse reactions in normal tissues.	price>
R-DS-0047	DSPE-PEG-iNGR(CRNGRGPDC)	LPNs were prepared with poly (histidine)(PHIS) as the core and di stearyl phosphatidylethanolamine polyethylene glycol (DSPE-PEG) and lecithin (EPC) as the single-layer shell.The anti-tumor drug DOX was encapsulated in LPNs and modified with the peptide ingr (crngrgpdc).	price>

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