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DSPE-PEG-c(RGDyK)
1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol-c(RGDyK)
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-DS-0046 | 50mg | 600.00 | + Add to cart |
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| R-DS-0046 | 100mg | 900.00 | + Add to cart |
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Product description
The immunogenicity of C (rgdyk)-peg-dspe was derived from C (rgdyk)-peg-dspe, which eventually led to serious life-threatening toxicity.However,C(rgdyk) itself had no ability to induce immune response.The results of antibody typing showed that IgG3 was the main subtype of specific IgG antibody of C (rgdyk) modified liposomes,and the antibody production rate was fast,suggesting that C (rgdyk) modified liposomes belonged to T cell independent type-2 (TI-2) antigen. At the same time,it was found that cytotoxic chemotherapeutic drugs could mask the immunogenicity of C (rgdyk) modified liposomes,but there might be safety problems when they were used to deliver molecular targeted drugs with good tumor cell specificity and low adverse reactions in normal tissues.
| Appearance | Off-white/brown solid or viscous liquid depends on molecular weight |
|---|---|
| PEG Molecular Weight | 1000,2000,3400,5000,10000 Dalton |
| substitution by NMR | >95% |
| PDI by GPC | <1.5 |
| Solubility | Organic solvents |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
Document
msds---DSPE-PEG-c(RGDyK) Related Product
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