Product apis-nf-kb

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Catalog	name	Description	price
R-R-1319	7-O-Methylaloesinol CAS No.105317-69-9	7-O-Methylaloesinol/CAS No.105317-69-9 is a chromone derivative. 7-O-Methylaloesinol shows significant inhibitory effects against TNFα-induced NF-κB transcriptional activity with an IC50 value of 29.07 μM.	price>
R-R-1320	Isoginkgetin CAS No.548-19-6	Isoginkgetin/CAS No.548-19-6 is a pre-mRNA splicing inhibitor inhibitor. Isoginkgetin also inhibits activities of both Akt, NF-κB and MMP-9. Isoginkgetin inhibits the activity of the 20S proteasome, induces apoptosis and activates autophagy.	price>
R-R-1321	18a-Glycyrrhetinic acid CAS No.1449-05-4	18α-Glycyrrhetinic acid/CAS No.1449-05-4, a diet-derived compound, is an inhibitor of NF-kB and an activator of proteasome, which serves as pro-longevity and anti-aggregation factor in a multicellular organism. 18α-Glycyrrhetinic acid induces apoptosis.	price>
R-R-1322	Sodium aescinate CAS No.20977-05-3	Sodium aescinate/CAS No.20977-05-3 is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities. Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway.	price>
R-R-1323	Geranylgeraniol CAS No.24034-73-9	Geranylgeraniol/CAS No.24034-73-9 is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model.	price>
R-R-1324	DMAPT CAS No.791595-09-0	DMAPT (Dimethylamino Parthenolide)/CAS No.791595-09-0, an analogue of Parthenolide (PTL), is an oral active NF-κB inhibitor, with a LD50 of 1.7 μM for cell population in AML cells. Has potential anti-cancer and anti-metastatic effect.	price>
R-R-1325	Ginsenoside Rk3 CAS No.364779-15-7	Ginsenoside Rk3/CAS No.364779-15-7 is present in the roots Panax ginseng herbs. Ginsenoside Rk3 significantly inhibits TNF-α-induced NF-κB transcriptional activity, with an IC50 of 14.24±1.30 μM in HepG2 cells.	price>
R-R-1326	Saikosaponin D CAS No.20874-52-6	Saikosaponin D/CAS No.20874-52-6 is a triterpene saponin isolated from Bupleurum, with anti-inflammatory, anti-bacterial, anti-tumor, and anti-allergic activities; Saikosaponin D inhibits selectin, STAT3 and NF-kB and activates estrogen receptor-β.	price>
R-R-1327	Parthenolide CAS No.20554-84-1	Parthenolide/CAS No.20554-84-1 is a sesquiterpene lactone found in the medicinal herb Feverfew. Parthenolide exhibits anti-inflammatory activity by inhibiting NF-κB activation; also inhibits HDAC1 protein without affecting other class I/II HDACs.	price>
R-R-1328	Isoliquiritin apioside CAS No.120926-46-7	Isoliquiritin apioside/CAS No.120926-46-7 significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced activation of MAPK and NF-κB. Isoliquiritin apioside auppresseses invasiveness and angiogenesis of cancer cells and endothelial cells.	price>

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