Product apis-membranet-transporters

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Catalog	name	Description	price
R-C-3185	KM 11060 CAS:774549-97-2	KM 11060 is a small molecule that corrects the processing of cystic fibrosis transmembrane conductance regulator (CFTR) proteins bearing the F508 deletion (F508del) mutation carried by 90% of cystic fibrosis patients.KM 11060 corrects F508del-CFTR trafficking, increasing the amount of functional CFTR at the plasma membrane (~75%) and Inhibits PDE5 activity.	price>
R-C-3186	GLPG2451 CAS:2055015-61-5	GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC50 of 11.1 nM.	price>
R-C-3187	Caldaret (MCC-135) CAS:133804-44-1	Caldaret is an intracellular Ca2+ handling modulator that acts through reverse mode Na+/Ca2+ exchanger inhibition.	price>
R-C-3188	TTA-Q6 CAS:910484-28-5	TTA-Q6 is a selective T-type Ca2+ channel antagonist, which can be used in the research of neurological disease.	price>
R-C-3189	GV-58 CAS:1402821-41-3	GV-58 is a potent, selective N- and P/Q-type Ca2+ channels agonist with EC50 of 7.21/8.81 uM for N-type/P-Q-type Ca2+ channel; 20-fold less potent CDK inhibitor activity.	price>
R-C-3190	Isradipine (Dynacirc) CAS:75695-93-1	Isradipine(PN 200-110)is a potent and selective L-type voltage-gated calcium channel blocker,used to treat high blood pressure.	price>
R-C-3192	Atagabalin CAS:223445-75-8	Atagabalin is related to gabapentin, which similarly binds to the α2δ calcium channels (1 and 2).	price>
R-C-3193	NNC 55-0396 CAS:357400-13-6	NNC 55-0396, Mibefradil derivative, is a highly selective T-type calcium channel blocker; displays IC50 values of 6.8 and>100μM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>
R-C-3195	Barnidipine CAS:104713-75-9	Barnidipine(Mepirodipine)is an L-type calcium antagonist(CaA)with high affinity for[3H]initrendipine binding sites(Ki=0.21nmol/l),has selective action against CaA receptors.Our products are only suitable for scientific research experiments,not for clinical experiments and human body.	price>
R-C-3196	Funapide CAS:1259933-16-8	Funapide(TV 45070;XEN402)is a potent Sodium Channel Nav1.7 inhibitor.Our products are only suitable for scientific research experiments, not for clinical experiments and human body.	price>

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