Product custom-nanocomposites-lipid-nanoparticle-composite-materials

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Catalog	name	Description	price
R-LCS30	Liposome-Ce6	Liposomes are small artificial vesicles of spherical shape that can be created from cholesterol and natural non-toxic phospholipids.Due to their size and hydrophobic and hydrophilic character(besides biocompatibility), liposomes are promising systems for drug delivery.Ce6 is a photosensitizer.1,2 It is active against S. aureus, P. aeruginosa, E.coli, and S. typhimurium when used at a concentration of 20 µM in combination with photodynamic therapy (PDT).	price>
R-M3-030	DOPC/CHOL Liposomes labeled with Fluorescein DHPE (100nm)	DOPC/CHOL Liposomes labeled with Fluorescein DHPE (100nm) is a type of liposome nanomaterial that can be used in fields such as Cell Imaging and Drug Delivery.Fluorescein DHPE: N-(fluorescein-5-thiocarbamoyl)-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine, triethylammonium salt.	price>
R-LCS31	Chitosan Hydrogel-Liposome	Chitosan is the only positive linear polysaccharide in nature. Its basic unit is glucosamine. Chitosan can form chemical gel with glutaraldehyde, and can also form physical gel with thioglycolic acid, acrylic acid, oxalic acid, etc.Liposomes are small artificial vesicles of spherical shape that can be created from cholesterol and natural non-toxic phospholipids.	price>
R-R-5665	HSPC/Chol/DSPE-mPEG2000/DSPE-mPEG2000-maleimide (50/45/4/1, mol/mol) Liposomes	HSPC/Chol/DSPE-mPEG2000/DSPE-mPEG2000-maleimide (50/45/4/1, mol/mol) Liposomes. PEGylated liposomes containing free maleimide functional group for maleimide-thiol conjugation. The liposomes are co-formulated with 1 mol% DSPE-mPEG2000-maleimide, and supplied in a pH-optimized buffer for direct conjugation of the thiol-containing molecule of choice. Conjugation can be achieved by incubating the liposomes with the activated thiol-containing compound which has been reduced by a disulfide bond reducing agent such as (tris(2-carboxyethyl)phosphine) (TCEP), which can be purchased as an add-on.	price>
R-R-5666	Tanespimycin (17-AAG) Liposomes, Formulation XT28.1	Tanespimycin (17-AAG) Liposomes, Formulation XT28.1. PEGylated liposomes containing Hsp90 inhibitor Tanespimycin (17-AAG). Tanespimycin exhibits 100-fold higher binding affinity to HSP90 derived from tumor cells vs normal cells, and induces apoptosis, necrosis, autophagy, and mitophagy. Tanespimycin is insoluble in aqueous media. This product is a pre-formulated liposomal version of Tanespimycin which is supplied ready to use in vitro or in vivo. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only.	price>
R-R-5667	DT-061 (SMAP) Liposomes, Formulation TT-40	DT-061 (SMAP) Liposomes, Formulation TT-40. PEGylated liposomes containing PP2A activator DT-061 (SMAP). DT-061 is an activator of protein phosphatase 2A (PP2A). PP2A regulates many cellular signaling pathways including MAPK/ERK, Wnt/β-catenin, Akt/mTOR, GSK3β, p53/apoptosis, cell cycle, and others. This product can be used in vitro or in vivo for studying the effects of PP2A activation and could be applied to preclinical therapy of KRAS-mutant and MYC-driven tumors. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only.	price>
R-R-5668	Liposomes for Loading Hydrophobic Drugs	Liposomes for Loading Hydrophobic Drugs (5.0mL). This pre-formed liposome product is created for post loading of hydrophobic small molecule compounds into liposomes. The process of drug incorporation is very straight-forward. Then simply add an aliquot of drug solution (prepared in a water-miscible solvent such as ethanol, DMSO and etc.) into the liposome suspension. The drug molecules can be incorporated into the lipid bilayers by the nature of hydrophobic interactions. The drug solubility therefore could be significantly enhanced. Liposomal drug concentration of 1-2 mg/mL could be achieved for most lipophilic drugs. PEGylation of the liposomes provides not only better formulation stability but also the potential of achieving prolonged in vivo blood circulation. The finished drug loaded formulations are suitable for either in vitro testing or in vivo studies.	price>
R-R-5669	HSPC/CHOL (55:45 mol/mol) Liposomes with Ammonium Sulfate Gradient (100nm)	HSPC/CHOL (55:45 mol/mol) Liposomes with Ammonium Sulfate Gradient (100nm). HSPC/CHO liposomes with ammonium gradient is the formulator choice for loading of weakly basic compounds, because it offers significantly improved drug retention and the ease of use in terms of process parameters such as loading temperature (60-70 deg C). One can use this liposomes as the placebo control for the drug loaded formulation or use the much cheaper plain HSPC/CHOL liposomes as placebo control.	price>
R-R-5670	DSPC/CHOL (55:45 mol/mol) Liposomes with Ammonium Sulfate Gradient (100nm)	DSPC/CHOL (55:45 mol/mol) Liposomes with Ammonium Sulfate Gradient (100nm). DSPC/CHO liposomes with ammonium gradient is the formulator choice for loading of weakly basic compounds, because it offers significantly improved drug retention and the ease of use in terms of process parameters such as loading temperature (60-70 deg C). One can use this liposomes as the placebo control for the drug loaded formulation or use the much cheaper plain DSPC liposomes as placebo control (F10203).	price>
R-R-5671	HSPC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol) Liposomes with Ammonium Sulfate Gradient (100nm)	HSPC/CHOL/mPEG-DSPE liposomes with ammonium gradient is the formulator choice in pharmaceutical/biotech industry for both formulation feasibility studies and liposomal product development, because HSPC is essentially equivalent to DSPC (HSPC contains about 85 % DSPC 15% DPPC). The main advantages for using HSPC are its lower cost and availability of GMP quality raw materials.	price>

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