Catalog name Description price
R-M2-10757 DBCO-Adamantane DBCO-Adamantane/Dibenzocyclooctyne-Adamantane is a linear bifunctional molecule. It can be applied to reversible labeling on cell surfaces, first fixing molecules by coupling DBCO with azide groups on the cell surface, and then visualizing cells by using adamantane combined with fluorescently labeled β - cyclodextrin. The reversible operation can be completed through competitive elution. It is also used for protein directed fixation, relying on the supramolecular interaction of adamantane/cyclodextrin to achieve controllable enzyme fixation, retaining biological activity while enhancing system stability. price>
R-M2-10773 DBCO-HA400K DBCO-Hyaluronic acid400k/Hyaluronic acid400k-DBCO/Dibenzocyclooctyne-Hyaluronic acid400k is a customized hyaluronic acid derivative designed for the field of bioorthogonal chemistry. As a bifunctional cross-linking unit, it reacts with other biological macromolecules modified by azide to prepare injectable, in-situ molded hyaluronic acid based smart hydrogels. Based on the CD44 targeting properties of HA and the click reaction activity of DBCO, targeted modification of nanocarriers is achieved to achieve precise drug delivery to tumor sites. It can be used to modify biological scaffold materials, enhance the biocompatibility and cell adhesion ability of the scaffold, and applied in areas such as cartilage repair and skin wound healing. price>
R-M2-10781 DBCO-Vancomycin Dibenzocyclooctyne-Vancomycin/Vancomycin-DBCO is a customized functional derivative designed for the fields of bioorthogonal chemistry and targeted antibacterial applications. Based on the Gram positive bacterial targeting properties of vancomycin and the click reaction activity of DBCO, specific fluorescent labeling and in vivo imaging of bacteria can be achieved by coupling with azide modified fluorescent dyes and nanoparticles. As a bifunctional cross-linking unit, it reacts with azide modified hydrogel and biological scaffold to prepare medical implant materials with long-term antibacterial properties for wound infection prevention and control. price>
R-M2-10796 DBCO-Dextran70k DBCO-Dextran70000/Dextran70k,DBCO labeled is a click chemistry functionalized macromolecular derivative obtained by covalently coupling dibenzocyclooctyne (DBCO) groups with 70kDa dextran as the backbone. price>
R-M2-10800 TCO-Diazirine-COOH TCO-Diazirine-COOH is a multifunctional photo crosslinking bioorthogonal reagent that simultaneously contains trans cyclooctene (TCO),bis (aziridine) photo crosslinking groups, and carboxyl groups.As a dual functional linking intermediate, a novel molecular probe with both in-situ capture and efficient enrichment functions is constructed by introducing photo crosslinking units and TCO bioorthogonal labels. price>
R-M2-10805 4-Guanidinobutanoic acid-N3 4-Guanidinobutanoic acid-N3/4-Guanidinobutanoic acid-Azide is a multifunctional click chemical intermediate with guanidine, carboxyl, and azide groups simultaneously. As a bifunctional linker, it couples with alkynyl/DBCO modified biomolecules through azide groups, introducing positively charged guanidine units on the molecule to regulate its cell penetration performance. As a small molecule probe, by clicking on reaction markers such as proteins and nucleic acids, and introducing guanidine tags, it enhances the specificity and efficiency of subsequent target enrichment. price>
R-M2-10812 DBCO-Ac4Man DBCO-Ac4Mannose/Dibenzocyclooctyne-Tetra-O-acetyl Mannose/DBCO-Acetylated 4 Mannose is a dual functional biomedical reagent designed specifically for copper free click chemistry mediated cell glucose metabolism markers. As a bifunctional linker, DBCO groups are introduced into glycosylated biomolecules, which are subsequently coupled with azide modified antibodies and drug molecules to construct targeted diagnostic and therapeutic integrated nanoprobes. It can be used for fluorescence labeling imaging of living cell sugar chains, glycoprotein enrichment analysis, copper free click chemical biological coupling, and in vivo level glucose metabolism tracking. price>
R-M-5169 Dibenzocyclooctyne-PEG750-cRGD DBCO-PEG750-cRGD,Dibenzocyclooctyne-polyethylene glycol750-cRGD from ruixi.cRGD is an active targeting chitosan modified by disulfide ring RGD peptide.Dibenzocyclooctyne (dbco) was used in the azido alkyne cycloaddition (spaac) reaction without copper ion catalysis.The kinetic constant of the second order reaction was 1.Dbco series products include dbco acid, dbco amine,dbco peg COOH,dbco peg amine,as well as dbco labeled biotin,fluorescent dyes and biochemical small molecules. price>