Catalog |
name |
Description |
price |
R-M-1270 |
STK11 Peptide |
STK11, a CAMK Ser/Thr protein kinase, has an essential role in G1 cell cycle arrest. STK11 phosphorylates and activates members of the AMPK-related subfamily of protein kinases. Defects in STK11 are a cause of predisposition to benign and maligant tumors including gastrointestinal and testicular cancers (Peutz-Jeghers syndrome). |
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R-M-1271 |
SPHK1 Peptide |
SPHK1 catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. |
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R-M-1272 |
SNAP43 Peptide |
The snRNA-activating protein complex 43 kDa subunit (SNAP43/SNAPC1/PTF) is part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. The SNAPc complex is composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAP43 is often found in OPT domain bodies, which contains several transcription factors (Oct1/PTF) and RNA transcripts, predominant in late G1 cells. OPT domain bodies localize close to the nucleolus. |
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R-M-1273 |
SNAIL Peptide |
SNAIL is involved in embryonic mesoderm formation by binding to 3 E-boxes of the E-cadherin gene promoter and repressing its transcription. |
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R-M-1277 |
SMURF1 Peptide |
SMURF1 peptide is used for blocking the activity of SMURF1 antibody.SMURF1 is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and directly transfers the ubiquitin to targeted substrates. SMURF1 interacts with receptor-regulated SMADs specific for the BMP pathway, SMAD1 and SMAD5, in order to trigger their ubiquitination and degradation. |
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R-M-1327 |
HGV-NS5 Peptide |
The non-structural protein 5 (NS5) from hepatitis G virus (HGV) is a helicase, an enzyme that unwinds nucleic acid duplexes with a distinct directional polarity. |
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R-M-1336 |
Hamartin Peptide |
Hamartin (TSC1) is involved in vesicular transport and docking with TSC2. Hamartin is a tumor suppressor. Defects in hamartin are the cause of tuberous sclerosis complex (TSC), a multi-system disorder. |
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R-M-1342 |
Glypican-3 Peptide |
Glypican-3 (GPC3) is a cell surface proteoglycan that bears heparan sulfate. GPC3 is likely involved in the modulation of growth in the predominantly mesodermal tissues and organs. Defects in GPC3 are the cause of pre- and postnatal overgrowth (gigantism, Simpson-Golabi-Behmel syndrome). |
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R-M-1400 |
CYLD Peptide |
CYLD is a negative regulator of TRAF2 and NF-kappa B signaling pathway. CYLD has a deubiquitinating activity that is directed towards non-Lys48-linked polyubiquitin chains. Defects in CYLD are the cause of familial cylindromatosis, a highly tumor type-specific disorder. |
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R-M-1420 |
CARP Peptide |
Catch-relaxing peptide (CARP) is isolated from Mytilus edulis (blue mussel). This peptide has a significant role in the regulation of muscle contraction. The peptide exhibits potentiating (contraction) and inhibitory (relaxation) effects on the anterior byssus retractor muscle. |
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