Catalog name Description price
R-R-0582 C- Myc peptide epitope c-Myc, the product of the c-myc proto-oncogene, is a helix-loop-helix leucine zipper phosphoprotein that regulates gene transcription in cell proliferation, cell differentiation and apoptosis. This peptide is a human c-myc epitope. price>
R-R-0592 Fas C-Terminal Tripeptide Fas C-Terminal Tripeptide/CAS:189109-90-8 from ruixi. This peptide corresponds to the C-terinal sequence of human Fas. It blocks the interaction of human Fas with Fas associated phosphatase-1 (FAP-1). price>
R-R-0871 Fmoc-Ala-Glu-Gln-Lys-NH2 Fmoc-Ala-Glu-Gln-Lys-NH2 (AEQK) is a tetrapeptide. Fmoc-Ala-Glu-Gln-Lys-NH2 is the inactive control for Fmoc-Ala-Glu-Asn-Lys-NH2 (AENK) peptide inhibitor. AENK blocks proteolysis of UNC5C protein. price>
R-R-0898 Ubrogepant Ubrogepant (MK-1602)/CAS No.1374248-77-7 is a novel oral calcitonin gene-related peptide receptor (CGRP) antagonist in development for acute treatment of migraine. price>
R-R-0904 Almorexant hydrochloride Almorexant (ACT 078573) hydrochloride/CAS No.913358-93-7 is an orally active, potent and competitive dual orexin receptor antagonist, with Kd values of 1.3 nM (OX1) and 0.17 nM (OX2), respectively. Almorexant hydrochloride reversibly blocks signaling of orexin-A and orexin-B peptides. Almorexant hydrochloride totally blocked the intracellular Ca2+ signal pathway. Almorexant hydrochloride stimulates caspase-3 activity in AsPC-1 cells and induces apoptosis. price>
R-R-0916 a-Bungarotoxin α-Bungarotoxin/CAS.11032-79-4 is a competitive antagonist at nicotinic acetylcholine receptors (nAChRs). α-Bungarotoxin, a selective α7 receptor blocker, blocks α7 currents with an IC50 of 1.6 nM and has no effects on α3β4 currents at concentrations up to 3 μM. price>
R-R-0973 Apelin-12 Apelin-12/CAS No.229961-08-4 is one of the most potent C-terminal fragments of the polypeptide that possesses a high affinity to orphan receptor APJ receptor. Apelin-12 is involved in the regulation of body fluid homeostasis and in the central control of feeding. Apelin-12 blocks HIV-1 entry through APJ receptor. Apelin-12 exerts neuroprotective effect. price>
R-M-182 XPA Peptide Xeroderma pigmentosum group A-complementing protein (XPA) is involved in DNA excision repair by binding to damaged sites with various affinities depending on photoadduct and transcriptional state. Defects in XPA are a cause of xeroderma pigmentosum complementation group A characterized by solar sensitivity and skin cancer predisposition.XPA is a zinc finger protein, which plays a central role in nucleotide excision repair (NER). XPA interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in XPA cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. price>
R-M-183 WT1 Peptide WT1,Wilms tumor 1 Peptide has a potential role in transcriptional regulation by recognizing and binding to the DNA sequence 5-CGCCCCCGC-3. Defects in WT1 are the cause of nephropathy (Frasier and Denys-Drash syndromes) and genito-urinary dysplasia in Wilms tumor syndrome.Data on WT1 peptide vaccine-treated patients with immunological and/or clinical response have been accumulated. MDS and acute myeloid leukemia were the major target diseases to provide proof of concept for the therapeutic potential of the WT1 peptide vaccine. WT1 vaccination-induced clinical responses or usefulness were also shown for chronic myeloid leukemia, multiple myeloma, and acute lymphoblastic leukemia, as well as various types of solid cancers.Patients with hematologic malignancies have minimal residual disease after chemotherapy or allogeneic hematopoietic stem cell transplantation, which can be treated by WT1 peptide vaccine. price>
R-M-184 WRN Peptide Werner syndrome ATP-dependent helicase (WRN) is essential for the formation of DNA replication focal centers and associates with foci elements generating binding sites for RPA. Defects in WRN are a cause of Werner syndrome, a multiple age-related disorders, including atherosclerosis, cancer, diabetes and osteoporosis. price>