Product apis-apoptosis

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Catalog	name	Description	price
R-R-1722	Girinimbine CAS No.23095-44-5	Girinimbine (Girinimbin)/CAS No.23095-44-5 is a carbazole alkaloid with a variety of biological effects. Girinimbine can induce apoptosis, and has antitrypanosomal, antiplatelet activity, antibacterial activity, anti-inflammatory, antioxidant and antitumor activities.	price>
R-R-1723	Tebufenozide CAS No.112410-23-8	Tebufenozide/CAS No.112410-23-8 is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells.	price>
R-R-1724	Ripretinib CAS No.1442472-39-0	Ripretinib (DCC-2618)/CAS No.1442472-39-0 is an orally bioavailable, selective KIT and PDGFRA switch-control inhibitor. Ripretinib (DCC-2618) targets and binds to both wild-type and mutant forms of KIT and PDGFRA specifically at their switch pocket binding sites, thereby preventing the switch from inactive to active conformations of these kinases and inactivating their wild-type and mutant forms. Ripretinib (DCC-2618) also inhibits multiple other kinase targets, such as FLT3 and KDR (or VEGFR-2). DCC-2618 exerts antineoplastic effect and induces apoptosis.	price>
R-R-1725	a-Eleostearic acid CAS No.506-23-0	α-Eleostearic acid (cis-Eleostearic acid)/CAS No.506-23-0, a conjugated linolenic acid, is an apoptosis inducer. α-Eleostearic acid is also a ferroptosis inducer. α-Eleostearic acid exhibits antioxidant and antitumor activity.	price>
R-R-1726	Kevetrin hydrochloride CAS No.66592-89-0	Kevetrin hydrochloride/CAS No.66592-89-0 is a potent activator of p53, induces apoptosis in TP53 wild-type and mutant acute myeloid leukemia cells. Kevetrin a preferential cytotoxic activity against blast cells.	price>
R-R-1727	Polyphyllin II CAS No.76296-72-5	Polyphyllin II/CAS No.76296-72-5 is one of the most significant saponins in Rhizoma Paridis and has toxic effects on kinds of cancer cells. Polyphyllin II induces apoptosis through caspases activation and cell-cycle arrest.	price>
R-R-1728	Anticancer agent 43 CAS No.2470015-35-9	Anticancer Agent 43/CAS No.2470015-35-9 is a potent anticancer agent. Anticancer Agent 43 induces apoptosis by caspase 3, PARP1, and Bax dependent mechanisms. Anticancer Agent 43 induces DNA damage.	price>
R-R-1729	Lumichrome CAS No.1086-80-2	Lumichrome/CAS No.1086-80-2, a photodegradation product of Riboflavin, is an endogenous compound in humans. Lumichrome inhibits human lung cancer cell growth and induces apoptosis via a p53-dependent mechanism.	price>
R-R-1730	Clofilium tosylate CAS No.92953-10-1	Clofilium tosylate/CAS No.92953-10-1, a potassium channel blocker, induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase-3. Antiarrhythmic agent.	price>
R-R-1731	Evocarpine CAS No.15266-38-3	Evocarpine/CAS No.15266-38-3, a quinolone alkaloid that could be isolated from Evodiae fructus, inhibitss Ca2+ influx through voltage-dependent calcium channels. Antimycobacterial activity.	price>

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