Product apis-apoptosis

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Catalog	name	Description	price
R-R-1712	Helichrysetin CAS No.62014-87-3	Helichrysetin/CAS No.62014-87-3 is isolated from the flower Helichrysum odoratissimum. Helichrysetin is an ID2 (DNA binding inhibitor 2) inhibitor. Helichrysetin induces apoptosis. Helichrysetin has anti-tumor and antioxidant activity.	price>
R-R-1713	Momordin Ic CAS No.96990-18-0	Momordin Ic/CAS No.96990-18-0 is a principal saponin constituent of Kochia scoparia L. Schrad. with anti-cancer bioactivity. Momordin Ic is also a SENP1 Inhibitor. Momordin Ic induces apoptosis through oxidative stress-regulated mitochondrial dysfunction.	price>
R-R-1714	Oxysophoridine CAS No.54809-74-4	Oxysophoridine (Sophoridine N-oxide)/CAS No.54809-74-4 is a bioactive alkaloid extracted from the Sophora alopecuroides Linn. Oxysophoridine (Sophoridine N-oxide) shows anti inflammatory, anti oxidative stress and anti apoptosis effects.	price>
R-R-1715	Dehydrotrametenolic acid CAS No.6879-05-6	Dehydrotrametenolic acid/CAS No.6879-05-6 is a sterol isolated from the sclerotium of Poria cocos. Dehydrotrametenolic acid induces apoptosis through caspase-3 pathway. Dehydrotrametenolic acid has anti-tumor activity, anti-inflammatory, anti-diabetic effects.	price>
R-R-1716	Neoxanthin CAS No.14660-91-4	Neoxanthin/CAS No.14660-91-4 is a major xanthophyll carotenoid and a precursor of the plant hormone abscisic acid in dark green leafy vegetables. Neoxanthin is a potent antioxidant and light-harvesting pigment. Neoxanthin induces apoptosis and has anticancer actions.	price>
R-R-1717	Zeylenone CAS No.193410-84-3	Zeylenone/CAS No.193410-84-3, a naturally occurring cyclohexene oxide, inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways.	price>
R-R-1718	7-epi-Isogarcinol CAS No.1141378-40-6	7-epi-Isogarcinol/CAS No.1141378-40-6 is a polycyclic polyprenylated acylphloroglucinol (PPAP), with moderate antiproliferative activity. 7-epi-Isogarcinol blocks STAT3 signaling pathway, to induce apoptosis and inhibit cell migration.	price>
R-R-1719	15-Acetoxyscirpenol CAS No.2623-22-5	15-acetoxyscirpenol/CAS No.2623-22-5, one of acetoxyscirpenol moiety mycotoxins (ASMs), strongly induces apoptosis and inhibits Jurkat T cell growth in a dose-dependent manner by activating other caspases independent of caspase-3.	price>
R-R-1720	Melatonin-d3 CAS No.90735-69-6	Melatonin-d3/CAS No.90735-69-6 is the deuterium labeled Melatonin. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation. Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress.	price>
R-R-1721	Clobenpropit dihydrobromide CAS No.145231-35-2	Clobenpropit dihydrobromide/CAS No.145231-35-2 is a potent histamine H3R antagonist/inverse agonist with a pEC50 of 8.07 for histamine H3LR. Clobenpropit dihydrobromide acts as partial agonist at histamine H4 receptors (Ki 13 nM). Clobenpropit dihydrobromide also binds to serotonin 5-HT3 receptors (Ki 7.4 nM) and α2A/α2C adrenoceptors (Ki 17.4/7.8 nM). Clobenpropit dihydrobromide increases apoptosis.	price>

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